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HNRNPH2

  • Official Full Name

    heterogeneous nuclear ribonucleoprotein H2 (H)

  • Overview

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.
  • Synonyms

    HNRNPH2; heterogeneous nuclear ribonucleoprotein H2 (H); HNRPH2; heterogeneous nuclear ribonucleoprotein H2; FTP3; hnRNPH; HNRPH; FTP-3; hnRNP H; hnRNP H2; heterogeneous nuclear ribonucleoprotein H-prime;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HNRNPH2-424H Recombinant Human HNRNPH2 Mammalian Cell His
Human HNRNPH2-4903H Recombinant Human HNRNPH2 Protein, GST-tagged Wheat Germ GST
Human HNRNPH2-5445HCL Recombinant Human HNRNPH2 293 Cell Lysate HEK293 N/A
Human HNRNPH2-3597HF Recombinant Full Length Human HNRNPH2 Protein, GST-tagged In Vitro Cell Free System GST 449 amino acids
Human HNRNPH2-4051H Recombinant Human HNRNPH2 protein, His&Myc-tagged E.coli His&Myc 1-449aa
Human HNRNPH2-6003H Recombinant Human HNRNPH2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HNRNPH2-1088H Recombinant Human HNRNPH2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HNRNPH2-1088H-B Recombinant Human HNRNPH2 Protein Pre-coupled Magnetic Beads HEK293
Human HNRNPH2-1914HFL Recombinant Full Length Human HNRNPH2 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Hnrnph2-3420M Recombinant Mouse Hnrnph2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat HNRNPH2-2883R Recombinant Rat HNRNPH2 Protein Mammalian Cell His
Rat HNRNPH2-2539R Recombinant Rat HNRNPH2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HNRNPH2-2539R-B Recombinant Rat HNRNPH2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HNRNPH2-2124R Recombinant Rhesus monkey HNRNPH2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HNRNPH2-1945R Recombinant Rhesus Macaque HNRNPH2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HNRNPH2-1945R-B Recombinant Rhesus Macaque HNRNPH2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HNRNPH2 involved in several pathways and played different roles in them. We selected most pathways HNRNPH2 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionAIMP2;ZNF454;IGF2BP3;ZNF256;SLC38A8;ZNF394;PSTPIP2;GPR19;TET3
Processing of Capped Intron-Containing Pre-mRNASF3B2;METTL3;WTAP;PAPOLA;TXNL4A;HNRNPH1;HNRNPD;METTL14;HNRNPA2B1
mRNA SplicingHNRNPA0B;PCBP2;HNRNPD;HNRNPL2;PTBP1B;SNRNP25;RNPC3;SFRS3A;HNRNPF
mRNA Splicing - Major PathwayTXNL4A;HNRNPA0B;HNRNPH2;HNRNPA2B1;PCBP2;YBX1;PTBP1B;CD2BP2;SF3A1
mRNA processingPRPF4B;METTL3;CELF1;SF3A1;PRMT2;HNRNPL;ZFP346;SF3B2;PRPF8

HNRNPH2 has several biochemical functions, for example, RNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPH2 itself. We selected most functions HNRNPH2 had, and list some proteins which have the same functions with HNRNPH2. You can find most of the proteins on our site.

Function Related Protein
RNA bindingSF1;PPP1R8;RBM14;PES;RTCA;RAE1;RBMS2;PUF60B;PAIP1
nucleotide bindingHELZ;FIGN;PABPC1L2A;RAB35B;GTF2F2B;CSNK1DB;HNRNPC;OXSR1A;GNAI2A
poly(A) RNA bindingRPUSD4;NUDT16L1;TCP1;DDX39;MRPS5;AKAP8;HIST1H1D;MKI67;SCG3
protein bindingHSPA1A;VSIG4;BAG4;ADRB2;RGMA;MAF;PRKCZ;BNIP3;MAPKAP1

HNRNPH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPH2.

TEKT1; MSI2; HNRNPA0; Ybx1; YWHAZ; RBFOX2; PQBP1; HSPB1; SNRPC; DDX5; GNB2L1; RBM10; ILF3; RBM39

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