Recombinant Human HNRNPH2 Protein, GST-tagged

• Cat.No.: HNRNPH2-4903H
• Product Overview: Human HNRNPH2 full-length ORF ( ADR82989.1, 1 a.a. - 449 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 49.4 kDa
• AA Sequence: MMLSTEGREGFVVKVRGLPWSCSAD EVMRFFSDCKIQNGTSGIRFIYTRE GRPSGEAFVELESEEEVKLALKKDR ETMGHRYVEVFKSNSVEMDWVLKHT GPNSPDTANDGFVRLRGLPFGCSKE EIVQFFSGLEIVPNGMTLPVDFQGR STGEAFVQFASQEIAEKALKKHKER IGHRYIEIFKSSRAEVRTHYDPPRK LMAMQRPGPYDRPGAGRGYNSIGRG AGFERMRRGAYGGGYGGYDDYGGYN DGYGFGSDRFGRDLNYCFSGMSDHR YGDGGSSFQSTTGHCVHMRGLPYRA TENDIYNFFSPLNPMRVHIEIGPDG RVTGEADVEFATHEDAVAAMAKDKA NMQHRYVELFLNSTAGTSGGAYDHS YVELFLNSTAGASGGAYGSQMMGGM GLSNQSSYGGPASQQLSGGYGGGYG GQSSMSGYDQVLQENSSDYQSNLA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H) [ Homo sapiens ]
• Official Symbol: HNRNPH2
• Synonyms: HNRNPH2; heterogeneous nuclear ribonucleoprotein H2 (H); HNRPH2; heterogeneous nuclear ribonucleoprotein H2; FTP3; hnRNPH; HNRPH; FTP-3; hnRNP H; hnRNP H2; heterogeneous nuclear ribonucleoprotein H-prime
• Gene ID: 3188
• mRNA Refseq: NM_001032393
• Protein Refseq: NP_001027565
• MIM: 300610
• UniProt ID: P55795