Recombinant Full Length Human HNRNPH2 Protein, C-Flag-tagged

• Cat.No.: HNRNPH2-1914HFL
• Product Overview: Recombinant Full Length Human HNRNPH2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 49.1 kDa
• AA Sequence: MMLSTEGREGFVVKVRGLPWSCSAD EVMRFFSDCKIQNGTSGIRFIYTRE GRPSGEAFVELESEEEVKLA LKKDRETMGHRYVEVFKSNSVEMDW VLKHTGPNSPDTANDGFVRLRGLPF GCSKEEIVQFFSGLEIVPNG MTLPVDFQGRSTGEAFVQFASQEIA EKALKKHKERIGHRYIEIFKSSRAE VRTHYDPPRKLMAMQRPGPY DRPGAGRGYNSIGRGAGFERMRRGA YGGGYGGYDDYGGYNDGYGFGSDRF GRDLNYCFSGMSDHRYGDGG SSFQSTTGHCVHMRGLPYRATENDI YNFFSPLNPMRVHIEIGPDGRVTGE ADVEFATHEDAVAAMAKDKA NMQHRYVELFLNSTAGTSGGAYDHS YVELFLNSTAGASGGAYGSQMMGGM GLSNQSSYGGPASQQLSGGY GGGYGGQSSMSGYDQVLQENSSDYQ SNLA TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 [ Homo sapiens (human) ]
• Official Symbol: HNRNPH2
• Synonyms: FTP3; MRXSB; NRPH2; HNRPH'; HNRPH2; hnRNPH'
• Gene ID: 3188
• mRNA Refseq: NM_019597.5
• Protein Refseq: NP_062543.1
• MIM: 300610
• UniProt ID: P55795