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HPS1

  • Official Full Name

    Hermansky-Pudlak syndrome 1

  • Overview

    This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene; the full-length sequences of some of these have not been determined yet.
  • Synonyms

    HPS1; Hermansky-Pudlak syndrome 1; Hermansky Pudlak syndrome , HPS; Hermansky-Pudlak syndrome 1 protein; Hermansky Pudlak syndrome 1 protein; Hermansky Pudlak syndrome gene; Hermansky Pudlak syndrome type 1; HPS; MGC5277; Hermansky-Pudlak syndrome type 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HPS1-5012H Recombinant Human HPS1 Protein, GST-tagged Wheat Germ GST
Human HPS1-13925H Recombinant Human HPS1, His-tagged E.coli His 1-324a.a.
Human HPS1-5397HCL Recombinant Human HPS1 293 Cell Lysate HEK293 N/A
Human HPS1-4535H Recombinant Human HPS1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HPS1-4739H Recombinant Human HPS1 protein, GST-tagged E.coli GST 1-324aa
Human HPS1-3629HF Recombinant Full Length Human HPS1 Protein, GST-tagged In Vitro Cell Free System GST 194 amino acids
Mouse HPS1-7833M Recombinant Mouse HPS1 Protein Mammalian Cell His
Mouse HPS1-4309M Recombinant Mouse HPS1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hps1-1857M Recombinant Mouse Hps1 protein, His & T7-tagged E.coli His/T7 Met1~Val275 (Accession # O08983)
Mouse HPS1-4309M-B Recombinant Mouse HPS1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Hps1-3435M Recombinant Mouse Hps1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish HPS1-3582Z Recombinant Zebrafish HPS1 Mammalian Cell His
Chicken HPS1-3221C Recombinant Chicken HPS1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HPS1 Related Articles

HPS1 involved in several pathways and played different roles in them. We selected most pathways HPS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HPS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HPS1 has several biochemical functions, for example, protein binding, protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HPS1 itself. We selected most functions HPS1 had, and list some proteins which have the same functions with HPS1. You can find most of the proteins on our site.

Function Related Protein
protein bindingDLG1;WNT2;UQCC1;SLC25A5;CBX1;PLD3;ZNF599;EMILIN1;TXNDC9
protein dimerization activityFERD3L;AIFM1;SCXB;STRA8;PPP3CB;POLR2J3;TCF21;OLIG4;HELT

HPS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HPS1.

HPS4; nhaA

Sarangarajan, R; Budev, A; et al. Abnormal translocation of tyrosinase and tyrosinase-related protein 1 in cutaneous melanocytes of Hermansky-Pudlak syndrome and in melanoma cells transfected with anti-sense HPS1 cDNA. JOURNAL OF INVESTIGATIVE DERMATOLOGY 117:641-646(2001).
  • Q&As
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