Recombinant Human HPS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HPS1-4535H
• Product Overview: HPS1 MS Standard C13 and N15-labeled recombinant protein (NP_872577) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on chromosome 22.
• Molecular Mass: 36.3 kDa
• AA Sequence: MKCVLVATEGAEVLFYWTDQEFEESLRLKFGQSENEEEELPALEDQLSTLLAPVIISSMTMLEKLSDTYTCFSTENGNFLYVLHLFGECLFIAINGDHTESEGDLRRKLYVLKYLFEVHFGLVTVDGHLIRKELRPPDLAQRVQLWEHFQSLLWTYSRLREQEQCFAVEALERLIHPQLCELCIEALERHVIQAVNTSPERGGEEALHAFLLVHSKLLAFYSSHSASSLRPADLLALILLVQDLYPSESTAEDDIQPSPRRARSSQNIPVQQAWSPHSTGPTGGSSAETETDSFSLPEEYFTPAPSPGDQSSGEDRRKAGGNNSTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HPS1 Hermansky-Pudlak syndrome 1 [ Homo sapiens (human) ]
• Official Symbol: HPS1
• Synonyms: HPS1; Hermansky-Pudlak syndrome 1; Hermansky Pudlak syndrome, HPS; Hermansky-Pudlak syndrome 1 protein; Hermansky-Pudlak syndrome type 1; HPS; MGC5277
• Gene ID: 3257
• mRNA Refseq: NM_182639
• Protein Refseq: NP_872577
• MIM: 604982
• UniProt ID: Q92902