Recombinant Human HPS1, His-tagged

• Cat.No.: HPS1-13925H
• Product Overview: Recombinant Human HPS1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-324a.a.
• Description: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Multiple transcript variants encoding distinct isoforms have been identified for this gene; the full-length sequences of some of these have not been determined yet.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HPS1 Hermansky-Pudlak syndrome 1 [ Homo sapiens ]
• Official Symbol: HPS1
• Synonyms: HPS1; Hermansky-Pudlak syndrome 1; Hermansky Pudlak syndrome , HPS; Hermansky-Pudlak syndrome 1 protein; Hermansky-Pudlak syndrome type 1; HPS; MGC5277
• Gene ID: 3257
• mRNA Refseq: NM_000195
• Protein Refseq: NP_000186
• MIM: 604982
• UniProt ID: Q92902
• Chromosome Location: 10q23.1-q23.3
• Function: protein binding; protein dimerization activity