itgb5
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  • Official Full Name
  • integrin, beta 5
  • Background
  • Integrin beta-5 is a protein that in humans is encoded by the ITGB5 gene.
  • Synonyms
  • ITGB5; integrin, beta 5; integrin beta-5; FLJ26658
Cat.#:ITGAV & ITGB5-758HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ITGAV & ITGB5 Protein, His-Avi-tagged, Biotinylated
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Cat.#:ITGB5-251HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ITGB5 Protein, His-tagged
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Cat.#:ITGB5-2645HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ITGB5 Protein, MYC/DDK-tagged
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Cat.#:ITGB5-4970HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ITGB5 Protein, GST-tagged
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Cat.#:Itgb5-252MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Itgb5 Protein, His-tagged
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Cat.#:ITGB5-8369MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ITGB5 Protein
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Cat.#:ITGB5-2316RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ITGB5 Protein, His-tagged
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Cat.#:ITGB5-6053CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ITGB5
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Cat.#:ITGB5-5232ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ITGB5
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Cat.#:ITGB5-880HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ITGB5 cell lysate
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Involved Pathway

ITGB5 involved in several pathways and played different roles in them. We selected most pathways ITGB5 participated on our site, such as Phagosome, PIK-Akt signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGB5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
CANX; ACTB; NOX3; BMA1; SEC61A1; TUBA1L; TUBA8L3; ATP6V0A1B; CLEC7A; FCGR2B
PIK-Akt signaling pathway
IFNA12; NRAS; MAPK1; TLR2; IL3RA; FGF2; PIK3CD; GNG11; PPP2R5E; Il4ra
Focal adhesion
RHOAB; PIK3R2; MAPK1; VCLA; HGF; RAC3A; PAK3; KDR; CHAD; PPP1CB
ECM-receptor interaction
ITGB4; ITGA7; GP1BB; ITGA9; COL4A5; LAMB2; ITGA4; DAG1; COL27A1B; TNR
Regulation of actin cytoskeleton
INS2; ITGA3B; F2R; CDC42; PIP5K1AA; PIP4K2AA; ENAH; ACTG1; PFN1; CFL2L
Proteoglycans in cancer
WNT3; TRP53; PPP1R12A; MAP2K1; ACTG1; PLCG2; ERBB4; ITPR3; WNT16; PIK3CA
Hypertrophic cardiomyopathy (HCM)
RYR2; ITGA3; PRKAG2; ITGA4; PRKAG1; ITGB5; CACNG7; CACNB3; MYBPC3; ITGA6
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ITGA7; ITGA1; RYR2; PKP2; CACNA2D1; CACNG6; SGCB; SGCD; ITGB5; LAMA2
Dilated cardiomyopathy
SGCA; CACNB1; ITGA3; TNNI3; SGCG; GNAS; ITGB4; CACNA2D3; SGCB; CACNG7

Protein Function

ITGB5 has several biochemical functions, for example, integrin binding, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGB5 itself. We selected most functions ITGB5 had, and list some proteins which have the same functions with ITGB5. You can find most of the proteins on our site.
Function
Related Protein
Function integrin binding
Related Protein ADAM10; TNN; ICAM3; WISP2; ADAM2; FCER2; ILK; FAP; EMP2; ADAMTS13
Function protein binding
Related Protein GRASP; FBXL3; LDB3; HEATR5B; DIEXF; PKP4; ZFP346; TBX5; NR1D1; SUV420H2
Function virus receptor activity
Related Protein TYRO3; SCARB2; AXL; HAVCR1; SCARB1; TFRC; SLC1A5; RPSA; SLAMF1; CXADR

Interacting Protein

ITGB5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGB5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGB5.
FRMD5; ANGPTL4; Myo7a; MYO10; ITGAV; Tln1