pdzk1
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  • Official Full Name
  • PDZ domain containing 1
  • Background
  • This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1.
  • Synonyms
  • PDZK1; PDZ domain containing 1; Na(+)/H(+) exchange regulatory cofactor NHE-RF3; NHERF3; PDZD1; naPi-Cap1; PDZ-containing kidney protein 1; CFTR-associated protein of 70 kDa; sodium-hydrogen exchanger regulatory factor 3; na/Pi cotransporter C-terminal-as
Cat.#:PDZK1-1075HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDZK1 Protein, MYC/DDK-tagged
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Cat.#:PDZK1-1633HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDZK1, GST-tagged
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Cat.#:PDZK1-30832THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PDZK1
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Cat.#:PDZK1-560HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDZ domain containing 1, His-tagged
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Cat.#:PDZK1-12613MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDZK1 Protein
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Cat.#:PDZK1-4365RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDZK1 Protein
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Cat.#:PDZK1-6965ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PDZK1
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Cat.#:PDZK1-477HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human PDZK1 lysate
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Protein Function

PDZK1 has several biochemical functions, for example, PDZ domain binding, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDZK1 itself. We selected most functions PDZK1 had, and list some proteins which have the same functions with PDZK1. You can find most of the proteins on our site.
Function
Related Protein
Function PDZ domain binding
Related Protein ACCN3; LRP2; FZD3; LIN7B; PLEKHA2; KCNJ4; EXOC4; TGFBR3; PARK2; TBC1D10A
Function protein binding
Related Protein HHEX; FAM118B; NOG; RAPGEF4; DEPDC6; ZZZ3; MAGEA2; OBFC1; LRSAM1; APP
Function protein complex binding
Related Protein C8B; MLC1; NCOA1; SLC9A3R1; FYB; CRHR1; AP2A2; VPS28; CRTAP; CDK5RAP2
Function scavenger receptor binding
Related Protein PDZK1
Function transporter activity
Related Protein SLC5A12; AQP8A.1; RBP5; CHP; FABP10A; DYF-1; SYPL2A; RBP2B; SLC4A11; IGF2R

Interacting Protein

PDZK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDZK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDZK1.
CFTR; BCR; GUCY2C; CLCN3; GFAP; PEX5; rep; ruvC; sucB; cirA1; tdh

PDZK1 Related Articles

Al-Jarallah, A; Chen, X; et al. High Density Lipoprotein Stimulated Migration of Macrophages Depends on the Scavenger Receptor Class B, Type I, PDZK1 and Akt1 and Is Blocked by Sphingosine 1 Phosphate Receptor Antagonists. PLOS ONE 9:-(2014).
O'Leary, PC; Penny, SA; et al. Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer. BMC CANCER 13:-(2013).