snap23
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  • Official Full Name
  • synaptosomal-associated protein, 23kDa
  • Background
  • Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein;termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with;SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general;membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most,;if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed;homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded;by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and;synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion;machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants;encoding different protein isoforms have been described for this gene.
  • Synonyms
  • SNAP23; synaptosomal-associated protein, 23kDa; synaptosomal associated protein, 23kD; synaptosomal-associated protein 23; HsT17016; SNAP23A; SNAP23B; vesicle-membrane fusion protein SNAP-23; SNAP-23
Cat.#:SNAP23-2832HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SNAP23, GST-tagged
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Cat.#:SNAP23-303HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Synaptosomal-associated Protein, 23kDa
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Cat.#:SNAP23-8116HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SNAP23 protein, His & T7-tagged
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Cat.#:SNAP23-15663MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SNAP23 Protein
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Cat.#:Snap23-8117MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Snap23 protein, His & T7-tagged
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Cat.#:SNAP23-5632RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SNAP23 Protein
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Cat.#:SNAP23-4357RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SNAP23 Protein, His-tagged
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Cat.#:SNAP23-4450CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SNAP23
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Cat.#:SNAP23-1641HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SNAP23 293 Cell Lysate
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Involved Pathway

SNAP23 involved in several pathways and played different roles in them. We selected most pathways SNAP23 participated on our site, such as SNARE interactions in vesicular transport, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNAP23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport
STX4A; STX5; STX7; BET1L; STX4; SNAP23.1; VTI1A; VAMP4; VAMP3; STX2
Platelet activation
PPP1CC; SRC; MYLK4; GNAS; PLCB3; FGA; FGB; PLA2G4C; FYN; SYK

Protein Function

SNAP23 has several biochemical functions, for example, SNAP receptor activity, protein binding, syntaxin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNAP23 itself. We selected most functions SNAP23 had, and list some proteins which have the same functions with SNAP23. You can find most of the proteins on our site.
Function
Related Protein
Function SNAP receptor activity
Related Protein VAMP1; BNIP1; VTI1A; STX10; STX11B.1; STX5AL; STX7; STX12; STX1A; SNAP29
Function protein binding
Related Protein KIF3B; LRRIQ3; ANKRD54; CD72; POLE4; UBXN6; GPR85; PCDH18; PTPN9; CLK2
Function syntaxin binding
Related Protein TMED10; TXLNBB; SNAP29; SYTL2; CPLX3A; SYT3; VPS52; NAPAB; RAB11A; NAPGA

Interacting Protein

SNAP23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNAP23 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNAP23.
STX11; VAMP3; NAPB; NAPA; ZDHHC17; NSF; VAMP7; PHF20L1

SNAP23 Related Articles

Gomez-Jaramillo, L; Delgado-Perez, L; et al. Syntaxin-4 is implicated in the secretion of antibodies by human plasma cells. JOURNAL OF LEUKOCYTE BIOLOGY 95:305-312(2014).
Chen, S; Barbieri, JT; et al. Engineering botulinum neurotoxin to extend therapeutic intervention. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 106:9180-9184(2009).