WFS1
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Official Full Name
Wolfram syndrome 1 (wolframin)
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Overview
Wolfram syndrome protein (WFS1) is an 890 amino acid protein that contains a cytoplasmic N-terminal domain, followed by nine-transmembrane domains and a luminal C-terminal domain. WFS1 is predominantly localized to the endoplasmic reticulum (ER) and its -
Synonyms
WFS1; Wolfram syndrome 1 (wolframin); DFNA6, DFNA14, DFNA38; wolframin; DIDMOAD; WFS; WFRS; WFSL; FLJ51211;
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- WFS1 Related Articles
- WFS1 Related Research Area
WFS1 involved in several pathways and played different roles in them. We selected most pathways WFS1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with WFS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein processing in endoplasmic reticulum | EIF2AK2;CUL1;PDIA6;DNAJC3A;RAD23B;CALRL2;HSPA5;RNF5;UBE2G1 |
WFS1 has several biochemical functions, for example, ATPase binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WFS1 itself. We selected most functions WFS1 had, and list some proteins which have the same functions with WFS1. You can find most of the proteins on our site.
Function | Related Protein |
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ATPase binding | RALB;PEX19;DNAJC10;SLN;SELS;ATP6V0A1A;DNAJB1;DERL1;USP25 |
protein binding | PTPRG;CCDC47;ETL4;CARKD;LRR1;TRIM74;ADAM33;BTBD1;SIX3 |
ubiquitin protein ligase binding | UBE2U;CUL3A;RPA2;UBE2NA;SQSTM1;HSPD1;RNF31;UBE2K;ABI2 |
WFS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WFS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of WFS1.
TERF1; ITGB3BP; MAPK6; CFTR
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