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CH25H

  • Official Full Name

    cholesterol 25-hydroxylase

  • Overview

    This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
  • Synonyms

    CH25H; cholesterol 25-hydroxylase; C25H; Cholesterol 25 hydroxylase; Cholesterol 25 monooxygenase; h25OH; OTTHUMP00000020057; cholesterol 25-monooxygenase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Danio rerio (Zebrafish) (Brachydanio rerio)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CH25H-11153H Recombinant Human CH25H, His-tagged E.coli His 140-272a.a.
Human CH25H-1196H Recombinant Human CH25H Protein, GST-Tagged Wheat Germ GST
Human CH25H-7549HCL Recombinant Human CH25H 293 Cell Lysate HEK293 N/A
Human CH25H-4169H Recombinant Human CH25H Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CH25H-588H Recombinant Human CH25H Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CH25H-1709HFL Recombinant Full Length Human CH25H Protein, C-Flag-tagged Mammalian cells Flag
Human CH25H-3305HF Recombinant Full Length Human CH25H Protein, GST-tagged In Vitro Cell Free System GST 272 amino acids
Human CH25H-771H Recombinant Human CH25H Protein, His-tagged E.coli N-His Trp142-Asn247
Human CH25H-588H-B Recombinant Human CH25H Protein Pre-coupled Magnetic Beads HEK293
Mouse CH25H-3361M Recombinant Mouse CH25H Protein Mammalian Cell His
Mouse CH25H-1619M Recombinant Mouse CH25H Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CH25H-1619M-B Recombinant Mouse CH25H Protein Pre-coupled Magnetic Beads HEK293
Mouse Ch25h-883M Recombinant Mouse Ch25h Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat CH25H-1360R Recombinant Rat CH25H Protein Mammalian Cell His
Rat CH25H-1018R Recombinant Rat CH25H Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CH25H-1018R-B Recombinant Rat CH25H Protein Pre-coupled Magnetic Beads HEK293
Danio rerio (Zebrafish) (Brachydanio rerio) RFL32780DF Recombinant Full Length Danio Rerio Cholesterol 25-Hydroxylase-Like Protein(Ch25H) Protein, His-Tagged E.coli expression system His Full Length (1-251)
Homo sapiens (Human) RFL10348HF Recombinant Full Length Human Cholesterol 25-Hydroxylase(Ch25H) Protein, His-Tagged E.coli expression system His Full Length (1-272)
Mus musculus (Mouse) RFL12708MF Recombinant Full Length Mouse Cholesterol 25-Hydroxylase(Ch25H) Protein, His-Tagged E.coli expression system His Full Length (1-298)
Rattus norvegicus (Rat) RFL33068RF Recombinant Full Length Rat Cholesterol 25-Hydroxylase(Ch25H) Protein, His-Tagged E.coli expression system His Full Length (1-298)
Rhesus Macaque CH25H-834R Recombinant Rhesus monkey CH25H Protein, His-tagged Mammalian Cell His
Rhesus Macaque CH25H-660R-B Recombinant Rhesus Macaque CH25H Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CH25H-660R Recombinant Rhesus Macaque CH25H Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Sus scrofa (Pig) RFL1992SF Recombinant Full Length Pig Cholesterol 25-Hydroxylase(Ch25H) Protein, His-Tagged E.coli expression system His Full Length (1-270)
Zebrafish CH25H-1937Z Recombinant Zebrafish CH25H Mammalian Cell His
Chicken CH25H-4771C Recombinant Chicken CH25H Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CH25H involved in several pathways and played different roles in them. We selected most pathways CH25H participated on our site, such as Primary bile acid biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CH25H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Primary bile acid biosynthesisCYP7B1;CYP39A1;SCP2;BAAT;CYP46A1.3;CYP8B1;HSD17B4;ACOX2;CYP46A1

CH25H has several biochemical functions, for example, cholesterol 25-hydroxylase activity, iron ion binding, steroid hydroxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CH25H itself. We selected most functions CH25H had, and list some proteins which have the same functions with CH25H. You can find most of the proteins on our site.

Function Related Protein
cholesterol 25-hydroxylase activityCH25H;BRSK2
iron ion bindingCYP2P9;LEPRE1;P4HA3;TYW5;ALOX12;LCN2;TMLHE;P3H2;CYP2A7
steroid hydroxylase activityCYP2J2;CYP2W1;CYP46A1.3;CYP2Y3;CYP2J6;CYP2C18;CYP2A4;CYP46A1;CYP2C55

CH25H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CH25H here. Most of them are supplied by our site. Hope this information will be useful for your research of CH25H.

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