Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512 Learn More

CRYBA4

Official Full Name

crystallin, beta A4
Overview

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the;major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens;central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout;life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma;families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided;into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting;peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the;C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of;different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins.;This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.
Synonyms

CRYBA4; crystallin, beta A4; beta-crystallin A4; Beta A4 crystallin; Beta crystallin A4; Beta-A4 crystallin; CRBA4_HUMAN; Crystallin beta A4; Eye lens structural protein; lens structural protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

E.coli
HEK293
Human
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CRYBA4-3607H	Recombinant Human CRYBA4, His-tagged	E.coli	His		Inquiry
Human	CRYBA4-4987H	Recombinant Human Crystallin, Beta A4, His-tagged	Human	His		Inquiry
Human	CRYBA4-1931H	Recombinant Human CRYBA4 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CRYBA4-7263HCL	Recombinant Human CRYBA4 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CRYBA4-301499H	Recombinant Human CRYBA4 protein, GST-tagged	E.coli	GST	Met1-Val44	Inquiry
Human	CRYBA4-2131HF	Recombinant Full Length Human CRYBA4 Protein, GST-tagged	In Vitro Cell Free System	GST	196 amino acids	Inquiry
Rat	CRYBA4-1612R	Recombinant Rat CRYBA4 Protein	Mammalian Cell	His		Inquiry
Rat	CRYBA4-1270R-B	Recombinant Rat CRYBA4 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	CRYBA4-1270R	Recombinant Rat CRYBA4 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	CRYBA4-2640Z	Recombinant Zebrafish CRYBA4	Mammalian Cell	His		Inquiry
Chicken	CRYBA4-5752C	Recombinant Chicken CRYBA4	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CRYBA4 involved in several pathways and played different roles in them. We selected most pathways CRYBA4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CRYBA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CRYBA4 has several biochemical functions, for example, molecular_function, protein binding, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by CRYBA4 itself. We selected most functions CRYBA4 had, and list some proteins which have the same functions with CRYBA4. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	PPP1R8B;SEBOX;ADAMTS16;RAD21L1;TNNT2D;GM1679;C21orf56;TUBA3B;ZNF705D
protein binding	TFAP2A;HSFX1;PDE2A;RAP1B;AKAP1;CUTC;MC1R;EFCAB4A;CD300LH
structural constituent of eye lens	CPOX;LIM2.5;LIM2.1;CRYBB2;LIM2.3;CRYAB;CRYABB;CRYGD;MIP

CRYBA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRYBA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRYBA4.

CEP76; CRYBB2; CRYBB1