Recombinant Human Crystallin, Beta A4, His-tagged

• Cat.No.: CRYBA4-4987H
• Product Overview: Recombinant human CRYBA4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: CRYBA4, also known as Beta-crystallin A4, belongs to the beta/gamma-crystallin family that are the dominant structural components of the vertebrate eye lens. Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.
• Concentration: 1.0 mg/ml
• Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, with 20% glycerol, 0.1M NaCl and 1mM DTT.
• Purity: > 95% by SDS - PAGE
• Sequence: 1-196 amino acids: MGSSHHHHHH SSGLVPRGSH MTLQCTKSAG PWKMVVWDED GFQGRRHEFT AECPSVLELG FETVRSLKVL SGAWVGFEHA GFQGQQYILE RGEYPSWDAW GGNTAYPAER LTSFRPAACA NHRDSRLTIF EQENFLGKKG ELSDDYPSLQ AMGWEGNEVG SFHVHSGAWV CSQFPGYRGF QYVLECDHHS GDYKHFREWG SHAPTFQVQS IRRIQ
• Molecular Mass: 24.5 kDa
• Applications: SDS PAGE
• Storage: Store at 4 deg C for short term storage. Aliquot and store at -20 deg C or -70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: CRYBA4 crystallin, beta A4 [ Homo sapiens ]
• Official Symbol: CRYBA4
• Synonyms: CRYBA4; MCOPCT4; beta-crystallin A4; OTTHUMP00000198864; beta-A4 crystallin; eye lens structural protein; crystallin, beta polypeptide A4
• Gene ID: 1413
• mRNA Refseq: NM_001886
• Protein Refseq: NP_001877
• MIM: 123631
• UniProt ID: P53673
• Chromosome Location: 22q11.2-q13.1; 22q12.1
• Function: molecular_function; structural constituent of eye lens