GABRB3
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Official Full Name
gamma-aminobutyric acid (GABA) A receptor, beta 3
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Overview
Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines. -
Synonyms
Gamma-aminobutyric acid type A receptors; GABAA receptors; GABRB3; gamma-aminobutyric acid (GABA) A receptor, beta 3; gamma-aminobutyric acid receptor subunit beta-3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- Mammalian cell
- Mammalian Cell
- Wheat Germ
- C
- StrepII
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Tag
- Free
- twin
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | GABRB3-28089TH | Recombinant Human GABRB3 | Wheat Germ | N/A | 110 amino acids | |
Human | GABRB3-6060HCL | Recombinant Human GABRB3 293 Cell Lysate | HEK293 | N/A | ||
Human | GABRB3-3749H | Recombinant Human GABRB3 protein, GST-tagged | E.coli | GST | 371-426 aa | |
Human | GABRB3-4647H | Recombinant Human GABRB3 Protein, GST-tagged | Wheat Germ | GST | ||
Human | GABRB3-05H | Recombinant Human GABRB3 Protein (M1-F332, SQPARAA, A447-N473 end), C-StrepII-tagged | Mammalian cell | C-StrepII | M1-F332, SQPARAA, A447-N473 end | |
Human | GABRB3-1550H | Recombinant Human GABRB3 Protein, His&GST-tagged | E.coli | N-His&GST | Gln26-Tyr245 | |
Human | GABRB3-0625H | Recombinant Human GABRB3 Protein (M1-F332, A447-N473 end), twin-StrepII tagged | Mammalian cell | twin-StrepII | M1-F332, A447-N473 end | |
Rat | GABRB3-2450R | Recombinant Rat GABRB3 Protein | Mammalian Cell | His | ||
Rat | GABRB3-2106R | Recombinant Rat GABRB3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | GABRB3-2106R-B | Recombinant Rat GABRB3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rattus norvegicus (Rat) | RFL28591RF | Recombinant Full Length Rat Gamma-Aminobutyric Acid Receptor Subunit Beta-3(Gabrb3) Protein, Tag-Free | E.coli expression system | Tag-Free | Full Length of Mature Protein (26-473) | |
Rhesus Macaque | GABRB3-1795R | Recombinant Rhesus monkey GABRB3 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | GABRB3-1616R-B | Recombinant Rhesus Macaque GABRB3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | GABRB3-1616R | Recombinant Rhesus Macaque GABRB3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Chicken | GABRB3-6898C | Recombinant Chicken GABRB3 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- GABRB3 Related Articles
- GABRB3 Related Research Area
GABRB3 involved in several pathways and played different roles in them. We selected most pathways GABRB3 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABRB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Neuroactive ligand-receptor interaction | GNRHR2;LPAR6;DRD1A;P2RX3;TSPO;PTGER1;FPR2;TAAR7F;P2RY10 |
Retrograde endocannabinoid signaling | PRKCG;GNAI1;GNG11;GNG2;GRIA1;MAPK11;GABRD;GABRA3;GNB3 |
Serotonergic synapse | CYP2C39;ALOX15;GNGT2;GNB3;MAPK3;CYP4X1;HTR3C;PLA2G4D;GABRB3 |
GABAergic synapse | GNG8;PLCL1;PRKACB;GLUL;GABRR2;PRKACG;GABARAPL1;GNAI2;GNG4 |
Nicotine addiction | GRIA4;GABRP;GRIN2C;GABRA3;GABRG1;GABRD;GRIA2;SLC17A7;GABRG3 |
GABRB3 has several biochemical functions, for example, GABA-A receptor activity, GABA-gated chloride ion channel activity, contributes_to chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GABRB3 itself. We selected most functions GABRB3 had, and list some proteins which have the same functions with GABRB3. You can find most of the proteins on our site.
Function | Related Protein |
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GABA-A receptor activity | GABRA1;GABRR2;GABRR3;GABRR2A;GABRG2;GABRE;GABRD;GABRB2;GABRB3 |
GABA-gated chloride ion channel activity | |
contributes_to chloride channel activity | GABRB2;BEST2;BEST4;GABRB1;GABRR3A;GABRQ;GABRR2A;BEST3;GABRB3 |
contributes_to extracellular ligand-gated ion channel activity | GABRQ;GABRR3A;GABRR2;GABRB1;GABRB2;GABRZ;GABRR2A;GABRB3 |
GABRB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABRB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABRB3.
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- Q&As
- Reviews
Q&As (7)
Ask a questionMutations and altered GABRB3 expression increase risk for autism and certain epilepsies.
GABRB3 is essential for inhibitory neurotransmission as part of the GABA-A receptor.
GABRB3 shows higher expression in early development, varying across stages.
GABRB3 knockout results in behavioral abnormalities and synaptic changes.
GABRB3 undergoes phosphorylation, impacting receptor activity.
Targeting GABRB3 may benefit disorders related to GABAergic dysfunction, like epilepsy and anxiety.
GABRB3 interacts with other GABA-A receptor subunits for proper function.
Customer Reviews (3)
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