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HMGCL

  • Official Full Name

    3-hydroxymethyl-3-methylglutaryl-CoA lyase

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HMGCL-13845H Recombinant Human HMGCL, His-tagged E.coli His 1-325a.a.
Human HMGCL-1562H Recombinant Human 3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase, His-tagged E.coli His
Human HMGCL-4874H Recombinant Human HMGCL Protein, GST-tagged Wheat Germ GST
Human HMGCL-5475HCL Recombinant Human HMGCL 293 Cell Lysate HEK293 N/A
Human HMGCL-4287H Recombinant Human HMGCL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGCL-3038H Recombinant Human HMGCL protein, GST-tagged E.coli GST 1-325aa
Human HMGCL-3647HF Recombinant Full Length Human HMGCL Protein, GST-tagged In Vitro Cell Free System GST 325 amino acids
Human HMGCL-211H Recombinant Human HMGCL Protein, His-tagged Insect Cell His 28-325aa
Mouse Hmgcl-8169M Recombinant Mouse Hmgcl protein, His & T7-tagged E.coli His/T7 Met1~Leu325 (Accession # P38060)
Mouse HMGCL-7732M Recombinant Mouse HMGCL Protein Mammalian Cell His
Mouse HMGCL-4239M-B Recombinant Mouse HMGCL Protein Pre-coupled Magnetic Beads HEK293
Mouse Hmgcl-1136M Recombinant Mouse Hmgcl Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HMGCL-4239M Recombinant Mouse HMGCL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HMGCL-2867R Recombinant Rat HMGCL Protein Mammalian Cell His
Rat HMGCL-2522R-B Recombinant Rat HMGCL Protein Pre-coupled Magnetic Beads HEK293
Rat HMGCL-2522R Recombinant Rat HMGCL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HMGCL-590C Recombinant Cynomolgus HMGCL Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HMGCL-336C Recombinant Cynomolgus Monkey HMGCL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HMGCL-336C-B Recombinant Cynomolgus Monkey HMGCL Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HMGCL-11427Z Recombinant Zebrafish HMGCL Mammalian Cell His
Chicken HMGCL-4211C Recombinant Chicken HMGCL Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HMGCL involved in several pathways and played different roles in them. We selected most pathways HMGCL participated on our site, such as Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGCL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Synthesis and degradation of ketone bodiesOXCT1;OXCT2B;BDH1;HMGCLL1;OXCT1B;OXCT2;OXCT2A;HMGCS1;ACAT2
Valine, leucine and isoleucine degradationALDH2.1;PCCB;MCCC2;HADHA;OXCT2;BCKDHA;ALDH3A2;BCKDHB;HMGCS1
Butanoate metabolismOXCT2;DHRS13L1;OXCT1A;OXCT1;GAD1B;OXCT2A;ECHS1;HMGCLL1;ACSM2B
Metabolic pathwaysDHODH;IL4I1;CYP2C18;MCEE;ITPKC;CYP19A1B;B4GALT6;PANK1B;INPP1
PeroxisomeMLYCD;ACSL3A;PEX19;ACSL4A;PEX11B;PEX5L;ACSL1B;PIPOX;DECR2

HMGCL has several biochemical functions, for example, carboxylic acid binding, fatty-acyl-CoA binding, hydroxymethylglutaryl-CoA lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGCL itself. We selected most functions HMGCL had, and list some proteins which have the same functions with HMGCL. You can find most of the proteins on our site.

Function Related Protein
carboxylic acid bindingAKR1C21;AKR1C2;PCK1;HIF1AN;GRHPR;HMGCL;GOT1
fatty-acyl-CoA bindingGCDHA;ACADSB;ACBD5;ACBD5A;ACBD3;ACADVL;DBIL5;HADHA;IVD
hydroxymethylglutaryl-CoA lyase activityHMGCLL1;HMGCL
magnesium ion bindingITPK1A;PRPS1A;ATP8A1;ENDOV;NT5C1BA;S100P;PKMA;PDXK;DIS3L2
manganese ion bindingPPM1AB;XPNPEP1;ABL1;LAP3;LARGE;SLC11A2;PEPD;DYRK2;ABL2
metal ion bindingTIMP4;KIT;CA4B;NUDT17;CCDC76;CECR1A;SMYD1B;HDAC7;GDPD3
protein homodimerization activityNRF1;GHR;DGCR8;BCL2;ENPP1;CTSE;WHRN;TCF4;NFKB1
receptor bindingCD70;CD72;TNFSF9;TNFSF4;NRG2;CCL13;F2;GLA;RND1

HMGCL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGCL here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGCL.

DNAJA1; GTF2B; HES1; ARL6IP1; q5ngc7_fratt; RNF126; MS4A7; ADAMTS10; SIRT4

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