Recombinant Full Length Human HMGCL Protein, GST-tagged
Cat.No. : | HMGCL-3647HF |
Product Overview : | Human HMGCL full-length ORF ( AAH10570, 1 a.a. - 325 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 61.49 kDa |
Protein Length : | 325 amino acids |
AA Sequence : | MAAMRKALPRRLVGLASLRAVSTSS MGTLPKRVKIVEVGPRDGLQNEKNI VSTPVKIKLIDMLSEAGLSVIETTS FVSPKWVPQMGDHTEVLKGIQKFPG INYPVLTPNLKGFEAAVAAGAKEVV IFGAASELFTKKNINCSIEESFQRF DAILKAAQSANISVRGYVSCALGCP YEGKISPAKVAEVTKKFYSMGCYEI SLGDTIGVGTPGIMKDMLSAVMQEV PLAALAVHCHDTYGQALANTLMALQ MGVSVVDSSVAGLGGCPYAQGASGN LATEDLVYMLEGLGIHTGVNLQKLL EAGNFICQALNRKTSSKVAQATCKL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase [ Homo sapiens ] |
Official Symbol : | HMGCL |
Synonyms : | HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase; hydroxymethylglutaryl-CoA lyase, mitochondrial; HL; hydroxymethylglutaricaciduria; HMG-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase; |
Gene ID : | 3155 |
mRNA Refseq : | NM_000191 |
Protein Refseq : | NP_000182 |
MIM : | 613898 |
UniProt ID : | P35914 |
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◆ Lysates | ||
HMGCL-5475HCL | Recombinant Human HMGCL 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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