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LAMTOR3

  • Official Full Name

    late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

  • Overview

    This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
  • Synonyms

    MP1; MAPBP; MAPKSP1; MAP2K1IP1; Ragulator3; ragulator complex protein LAMTOR3; PRO0633; MEK partner 1; OTTHUMP00000161681; OTTHUMP00000219461; MEK binding partner 1; MEK-binding partner 1; MAPK scaffold protein 1; mitogen-activated protein kinase scaffold protein 1; late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; mitogen-activated protein kinase kinase 1 interacting protein 1; mitogen-activated protein kinase kinase 1-interacting protein 1; LAMTOR3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Human
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LAMTOR3-5066H Recombinant Human Late Endosomal/Lysosomal Adaptor And MAPK And MTOR Activator 3, His-tagged Human N/A
Human LAMTOR3-523H Recombinant Human LAMTOR3 Protein, His-tagged E.coli His
Human LAMTOR3-28221TH Recombinant Human LAMTOR3, His-tagged E.coli His 124 amino acids
Human LAMTOR3-4482HCL Recombinant Human MAPKSP1 293 Cell Lysate HEK293 N/A
Human LAMTOR3-5231H Recombinant Human LAMTOR3 Protein (Met1-Ser124), His tagged E.coli His Met1-Ser124
Human LAMTOR3-3207H Recombinant Human LAMTOR3 protein, GST-tagged E.coli GST 1-124aa
Mouse LAMTOR3-8945M Recombinant Mouse LAMTOR3 Protein Mammalian Cell His
Mouse LAMTOR3-4988M Recombinant Mouse LAMTOR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LAMTOR3-4988M-B Recombinant Mouse LAMTOR3 Protein Pre-coupled Magnetic Beads HEK293
Rat LAMTOR3-3352R Recombinant Rat LAMTOR3 Protein Mammalian Cell His
Rat LAMTOR3-3008R Recombinant Rat LAMTOR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LAMTOR3-3008R-B Recombinant Rat LAMTOR3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LAMTOR3-2757Z Recombinant Zebrafish LAMTOR3 Mammalian Cell His
Chicken LAMTOR3-1696C Recombinant Chicken LAMTOR3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

LAMTOR3 involved in several pathways and played different roles in them. We selected most pathways LAMTOR3 participated on our site, such as MAPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMTOR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayRAC1B;CACNB1;Fasl;GNA12;PLA2G4C;MAP3K7;PPM1NB;RPS6KAL;MAPK10

LAMTOR3 has several biochemical functions, for example, contributes_to guanyl-nucleotide exchange factor activity, protein binding, contributes_to protein complex scaffold. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMTOR3 itself. We selected most functions LAMTOR3 had, and list some proteins which have the same functions with LAMTOR3. You can find most of the proteins on our site.

Function Related Protein
contributes_to guanyl-nucleotide exchange factor activityEIF2B1;LAMTOR3;C7orf59;EIF2B5;HBXIP;EIF2B4;ALS2;EIF2B3;LAMTOR2
protein bindingLYAR;P2RY6;CD44;FAH;UBE2O;MPDU1;HAND1;APLP2;FBF1
contributes_to protein complex scaffoldHBXIP;LAMTOR3;C7orf59;LAMTOR1;LAMTOR2

LAMTOR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMTOR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMTOR3.

LAMTOR2; RRAGB; RRAGC

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