Recombinant Human Late Endosomal/Lysosomal Adaptor And MAPK And MTOR Activator 3, His-tagged

• Cat.No.: LAMTOR3-5066H
• Product Overview: Recombinant human LAMTOR3protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: Non
• Description: LAMTOR3(Mitogen-activated protein kinase scaffold protein 1) is a scaffold proteinthat functions in the extracellular signal-regulated kinase (ERK) cascade.The protein is localized to late endosomes by the mitogen-activatedprotein-binding protein-interacting protein, and binds specifically to MAPkinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.
• Form: Supplied as aliquid in 20 mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 5 mM DTTand 100 mM NaCl.
• Purity: > 95% by SDS-PAGE
• Concentration: 0.5 mg/ml
• Sequence: 1-124 amino acids:MGSSHHHHHH SSGLVPRGSH MADDLKRFLY KKLPSVEGLH AIVVSDRDGV PVIKVANDNA PEHALRPGFLSTFALATDQG SKLGLSKNKS IICYYNTYQV VQFNRLPLVV SFIASSSANT GLIVSLEKEL APLFEELRQVVEVS
• Molecular Mass: 15.8 kDa(144aa) confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Store at 4 deg Cfor short term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 degC for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: LAMTOR3

Gene Information

• Gene Name: LAMTOR3 late endosomal/lysosomaladaptor, MAPK and MTOR activator 3 [ Homo sapiens ]
• Synonyms: LAMTOR3; lateendosomal/lysosomal adaptor and MAPK and MTOR activator 3; MP1; MAPBP;MAPKSP1; MAP2K1IP1; Regulator3; ragulator complex protein LAMTOR3; PRO0633;MEK partner 1; OTTHUMP00000161681; OTTHUMP00000219461; MEK binding partner 1;MEK-binding partner 1; MAPK scaffold protein 1; mitogen-activated proteinkinase scaffold protein 1; mitogen-activated protein kinase kinase 1interacting protein 1; mitogen-activated protein kinase kinase 1-interactingprotein 1
• Gene ID: 8649
• mRNA Refseq: NM_021970
• Protein Refseq: NP_068805
• MIM: 603296
• UniProt ID: Q9UHA4
• Chromosome Location: 4q24-q26
• Pathway: MAPK signalingpathway