Recombinant Human LAMTOR3 Protein (Met1-Ser124), His tagged

Cat.No. : LAMTOR3-5231H
Product Overview : Recombinant human LAMTOR3 (Met1-Ser124) fused with His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : Met1-Ser124
Description : As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Form : Lyophilized powder/frozen liquid
Molecular Mass : 15.14 kDa
Purity : >90% as determined by SDS-PAGE.
Notes : For research use only.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer : Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
Reconstitution : Reconstitute in sterile water for a stock solution.
Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Name LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 [ Homo sapiens (human) ]
Official Symbol LAMTOR3
Synonyms LAMTOR3; late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; MAP2K1IP1, MAPK scaffold protein 1, MAPKSP1, mitogen activated protein kinase kinase 1 interacting protein 1; ragulator complex protein LAMTOR3; MAPBP; MEK partner 1; MP1; Ragulator3; MEK binding partner 1; MAPK scaffold protein 1; mitogen-activated protein kinase scaffold protein 1; late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; mitogen-activated protein kinase kinase 1 interacting protein 1; MAPKSP1; PRO0633; MAP2K1IP1;
Gene ID 8649
mRNA Refseq NM_001243736
Protein Refseq NP_001230665
MIM 603296
UniProt ID Q9UHA4

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