LPXN
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Official Full Name
leupaxin
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Overview
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. -
Synonyms
LPXN; leupaxin; LDPL; LDLP;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | LPXN-4661HCL | Recombinant Human LPXN 293 Cell Lysate | HEK293 | N/A |
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| Human | LPXN-4712H | Recombinant Human LPXN Protein, GST-tagged | Wheat Germ | GST |
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| Human | LPXN-6000HF | Recombinant Full Length Human LPXN Protein, GST-tagged | In Vitro Cell Free System | GST | 386 amino acids |
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| Human | LPXN-1663H | Recombinant Human LPXN protein, His & T7-tagged | E.coli | His/T7 | Met1~Gln205 (Accession # O60711) |
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| Mouse | Lpxn-7898M | Recombinant Mouse Lpxn protein, His & T7-tagged | E.coli | His/T7 | Met1~Ser208 (Accession # Q99N69) |
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| Mouse | LPXN-9208M | Recombinant Mouse LPXN Protein | Mammalian Cell | His |
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| Mouse | LPXN-5145M-B | Recombinant Mouse LPXN Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | LPXN-5145M | Recombinant Mouse LPXN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | LPXN-2545R | Recombinant Rhesus monkey LPXN Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | LPXN-2365R | Recombinant Rhesus Macaque LPXN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | LPXN-2365R-B | Recombinant Rhesus Macaque LPXN Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- LPXN Related Articles
LPXN involved in several pathways and played different roles in them. We selected most pathways LPXN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LPXN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
LPXN has several biochemical functions, for example, protein binding, transcription cofactor activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LPXN itself. We selected most functions LPXN had, and list some proteins which have the same functions with LPXN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PRPS2;NEK6;CRYAA;UBA5;LRR1;DACT1;RHOG;CNTROB;RTN4 |
| transcription cofactor activity | THRAP3;AIRE;NFE2L1;NSD1;ANKRA2;CREB1;ZNF710A;NRG1;MED24 |
| zinc ion binding | APOBEC1;MANEA;ARHGEF2;PAPLNB;GATA4;DTNB;NR4A2;C6AST4;MTA2 |
LPXN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPXN here. Most of them are supplied by our site. Hope this information will be useful for your research of LPXN.
Hoxa1; 9814; LMO1; HOXC9; RUNX1T1; PLEKHN1; DKFZp451B226
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