Recombinant Human LPXN Protein, GST-tagged

• Cat.No.: LPXN-4712H
• Product Overview: Human LPXN full-length ORF ( AAH19035, 1 a.a. - 386 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 68.20 kDa
• AA Sequence: MEELDALLEELERSTLQDSDEYSNP APLPLDQHSRKETNLDETSEILSIQ DNTSPLPAQLVYTTNIQELNVYSEA QEPKESPPPSKTSAAAQLDELMAHL TEMQAKVAVRADAGKKHLPDKQDHK ASLDSMLGGLEQELQDLGIATVPKG HCASCQKPIAGKVIHALGQSWHPEH FVCTHCKEEIGSSPFFERSGLAYCP NDYHQLFSPRCAYCAAPILDKVLTA MNQTWHPEHFFCSHCGEVFGAEGFH EKDKKPYCRKDFLAMFSPKCGGCNR PVLENYLSAMDTVWHPECFVCGDCF TSFSTGSFFELDGRPFCELHYHHRR GTLCHGCGQPITGRCISAMGYKFHP EHFVCAFCLTQLSKGIFREQNDKTY CQPCFNKLFPL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LPXN leupaxin [ Homo sapiens ]
• Official Symbol: LPXN
• Synonyms: LPXN; leupaxin; LDPL
• Gene ID: 9404
• mRNA Refseq: NM_001143995
• Protein Refseq: NP_001137467
• MIM: 605390
• UniProt ID: O60711