| Species : |
Human |
| Source : |
E.coli |
| Tag : |
His&T7 |
| Protein Length : |
Met1~Gln205 |
| Description : |
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Form : |
Freeze-dried powder |
| Molecular Mass : |
33kDa as determined by SDS-PAGE reducing conditions. |
| Endotoxin : |
<1.0EU per 1ug (determined by the LAL method) |
| Purity : |
>90% |
| Applications : |
SDS-PAGE; WB; ELISA; IP. |
| Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Storage buffer : |
Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
| Reconstitution : |
Reconstitute in sterile ddH2O. |
| Isoelectric Point : |
4.8 |
