NUDT3
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Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 3
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Overview
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 -
Synonyms
NUDT3; nudix (nucleoside diphosphate linked moiety X)-type motif 3; diphosphoinositol polyphosphate phosphohydrolase 1; DIPP; Diadenosine 5 5 P1 P6 hexaphosphate hydrolase 1; Diphosphoinositol polyphosphate phosphohydrolase; DIPP 1; DIPP1; Nucleoside diphosphate linked moiety X motif 3; Nudix (nucleoside diphosphate linked moiety X) type motif 3; Nudix motif 3; Nudix type motif 3; NUDT 3; OTTHUMP00000016227; nucleoside diphosphate-linked moiety X motif 3; diadenosine 5,5-P1,P6-hexaphosphate hydrolase 1; DIPP-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E. coli
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- NUDT3 Related Articles
NUDT3 involved in several pathways and played different roles in them. We selected most pathways NUDT3 participated on our site, such as Inositol phosphate metabolism, Metabolism, Synthesis of pyrophosphates in the cytosol, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Inositol phosphate metabolism | PIK3CD;PIP5K1A;PIP5K1AA;ITPK1;PLCG1;PLCB3;PIP4K2A;PIP5K2;ITPKB |
Metabolism | CPTP;CYP2U1;SLC27A2A;SLC25A11;HPSE;DECR1;PIK3R6;CYP19A1;MTP |
Synthesis of pyrophosphates in the cytosol | NUDT11;NUDT4B;NUDT10;IP6K3;NUDT3A;NUDT3B;NUDT4A;NUDT3;NUDT4 |
NUDT3 has several biochemical functions, for example, diphosphoinositol-polyphosphate diphosphatase activity, inositol diphosphate tetrakisphosphate diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT3 itself. We selected most functions NUDT3 had, and list some proteins which have the same functions with NUDT3. You can find most of the proteins on our site.
Function | Related Protein |
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diphosphoinositol-polyphosphate diphosphatase activity | NUDT3;NUDT4;NUDT10;NUDT11 |
inositol diphosphate tetrakisphosphate diphosphatase activity | NUDT4;NUDT11;NUDT3;NUDT10 |
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity | NUDT4;NUDT10;NUDT11;NUDT3 |
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity | NUDT3;NUDT11;NUDT10;NUDT4 |
inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity | NUDT3;NUDT4;NUDT11;NUDT10 |
inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity | NUDT11;NUDT4;NUDT3;NUDT10 |
inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity | NUDT10;NUDT3;NUDT4;NUDT11 |
inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity | NUDT11;NUDT4;NUDT3;NUDT10 |
magnesium ion binding | ATP9B;ADPRH;SERPINB1A;ENO4;CDC42BPG;PDXP;THG1L;ATP11C;ATP8B5 |
NUDT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT3.
RPLP1; ASB13; PDCD5; PRKD3; SOX30; OAT; NR2C1; ALAS1; RPL17; EEF1G; APEX1; DNAJA1; MCM5; TNNT3; PEX5; CCL11; RPL8; REEP5
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