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NUDT3

  • Official Full Name

    nudix (nucleoside diphosphate linked moiety X)-type motif 3

  • Overview

    NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998
  • Synonyms

    NUDT3; nudix (nucleoside diphosphate linked moiety X)-type motif 3; diphosphoinositol polyphosphate phosphohydrolase 1; DIPP; Diadenosine 5 5 P1 P6 hexaphosphate hydrolase 1; Diphosphoinositol polyphosphate phosphohydrolase; DIPP 1; DIPP1; Nucleoside diphosphate linked moiety X motif 3; Nudix (nucleoside diphosphate linked moiety X) type motif 3; Nudix motif 3; Nudix type motif 3; NUDT 3; OTTHUMP00000016227; nucleoside diphosphate-linked moiety X motif 3; diadenosine 5,5-P1,P6-hexaphosphate hydrolase 1; DIPP-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NUDT3-3476H Recombinant Human NUDT3, His-tagged E.coli His
Human NUDT3-1406H Recombinant Human NUDT3, GST-tagged E.coli GST 1-172aa
Human NUDT3-27534TH Recombinant Human NUDT3, His-tagged E.coli His 172 amino acids
Human NUDT3-1227HCL Recombinant Human NUDT3 cell lysate N/A
Human NUDT3-376H Recombinant Human NUDT3 protein, His-tagged E. coli His 1-172 aa
Human NUDT3-3144H Recombinant Human NUDT3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NUDT3-30117H Recombinant Human NUDT3 protein, GST-tagged E.coli GST Met1-Arg172
Mouse NUDT3-10974M Recombinant Mouse NUDT3 Protein Mammalian Cell His
Mouse NUDT3-6258M Recombinant Mouse NUDT3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nudt3-4541M Recombinant Mouse Nudt3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NUDT3-6258M-B Recombinant Mouse NUDT3 Protein Pre-coupled Magnetic Beads HEK293
Rat NUDT3-4118R Recombinant Rat NUDT3 Protein Mammalian Cell His
Rat NUDT3-3779R Recombinant Rat NUDT3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NUDT3-3779R-B Recombinant Rat NUDT3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque NUDT3-3128R Recombinant Rhesus monkey NUDT3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NUDT3-2946R Recombinant Rhesus Macaque NUDT3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NUDT3-2946R-B Recombinant Rhesus Macaque NUDT3 Protein Pre-coupled Magnetic Beads HEK293
Chicken NUDT3-4619C Recombinant Chicken NUDT3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NUDT3 Related Articles

NUDT3 involved in several pathways and played different roles in them. We selected most pathways NUDT3 participated on our site, such as Inositol phosphate metabolism, Metabolism, Synthesis of pyrophosphates in the cytosol, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inositol phosphate metabolismPLCB1;PIP5K1C;MTMR8;PLCH2;PI4KAA;MINPP1;NUDT4A;PIK3C2B;PIP4K2B
MetabolismPEMT;FA2H;GLTPA;NFYAL;CYP2R1;CYGB2;CD320;SLC19A2;CYP17A1
Synthesis of pyrophosphates in the cytosolIP6K3;NUDT3B;NUDT4A;NUDT11;NUDT3A;NUDT4;NUDT3;NUDT4B;NUDT10

NUDT3 has several biochemical functions, for example, diphosphoinositol-polyphosphate diphosphatase activity, inositol diphosphate tetrakisphosphate diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT3 itself. We selected most functions NUDT3 had, and list some proteins which have the same functions with NUDT3. You can find most of the proteins on our site.

Function Related Protein
diphosphoinositol-polyphosphate diphosphatase activityNUDT4;NUDT3;NUDT11;NUDT10
inositol diphosphate tetrakisphosphate diphosphatase activityNUDT11;NUDT3;NUDT10;NUDT4
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activityNUDT4;NUDT10;NUDT3;NUDT11
inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activityNUDT10;NUDT3;NUDT4;NUDT11
inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activityNUDT10;NUDT11;NUDT3;NUDT4
inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activityNUDT3;NUDT10;NUDT4;NUDT11
inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activityNUDT10;NUDT11;NUDT4;NUDT3
inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activityNUDT3;NUDT11;NUDT4;NUDT10
magnesium ion bindingATP8A1;ZNF143B;PKLR;STK36;PKM;PPA2;ABL1;CERK;ABL2

NUDT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT3.

RPLP1; ASB13; PDCD5; PRKD3; SOX30; OAT; NR2C1; ALAS1; RPL17; EEF1G; APEX1; DNAJA1; MCM5; TNNT3; PEX5; CCL11; RPL8; REEP5

Albayrak, O; Putter, C; et al. Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 162B:295-305(2013).
Wilson, GRS; Morton, JD; et al. The locus for an inherited cataract in sheep maps to ovine chromosome 6. MOLECULAR VISION 18:1384-1394(2012).
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