PLA2G1B Protein, phospholipase A2, group IB (pancreas)


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Official Full Name phospholipase A2, group IB (pancreas)
Background Phospholipase A2 (EC catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known;varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2;enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to;venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine,;macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986;(PubMed 3028739)) .
Synonyms PLA2G1B; phospholipase A2, group IB (pancreas); PLA2, PLA2A, PPLA2; phospholipase A2; group IB phospholipase A2; phosphatidylcholine 2-acylhydrolase 1B; PLA2; PLA2A; PPLA2; MGC119834; MGC119835
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PLA2G1B-171H Recombinant Human PLA2G1B protein, His-tagged HEK293 His
    Human PLA2G1B-1751H Recombinant Human PLA2G1B, His-tagged E.coli His
    Human PLA2G1B-1878H Recombinant Human PLA2G1B Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PLA2G1B-2200HCL Recombinant Human PLA2G1B cell lysate Human Cell N/A
    Human PLA2G1B-254H Recombinant Human PLA2G1B Protein, His-tagged HEK293 His
    Human PLA2G1B-31023TH Recombinant Human PLA2G1B, His-tagged E.coli His
    Human PLA2G1B-625H Recombinant Human PLA2G1B, His-tagged NS0 His
    Human PLA2G1B-66H Recombinant Human Phospholipase A2, Group IB (Pancreas), His-tagged E.coli His
    Mouse Pla2g1b-1185M Recombinant Mouse Pla2g1b, His tagged Human Cell His
    Mouse PLA2G1B-2033MCL Recombinant Mouse PLA2G1B cell lysate Human Cell N/A
    Rat PLA2G1B-4487R Recombinant Rat PLA2G1B Protein Mammalian Cell His
    Chicken PLA2G1B-3919C Recombinant Chicken PLA2G1B Mammalian Cell His

    PLA2G1B involved in several pathways and played different roles in them. We selected most pathways PLA2G1B participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid metabolism AGPAT9L; LPGAT1; GPAT2; CDS2; PLA2G2D; PCYT1BA; PLA2G4F; GPD1A; GPD2; CHAT
    Ether lipid metabolism ENPP6; PLB1; PLA2G1B; PLD1A; PAFAH1B1B; PLA2G4AA; PLA2G4D; LPCAT2; PPAP2D; GAL3ST1A
    Arachidonic acid metabolism LTC4S; CYP2C54; CBR1; PLA2G4A; ALOX15; AKR1C6; CBR3; CYP2V1; PTGES3A; CYP2Y3
    Linoleic acid metabolism CYP2P10; CYP2C70; PLA2G4C; PLA2G10; PLA2G2A; PLA2G4D; CYP3A65; CYP2C45; PLA2G1B; PLA2G4A
    alpha-Linolenic acid metabolism PLA2G5; ACAA1A; ACAA1; PLA2G2D; FADS2; PLA2G4F; ACOX3; PLA2G4AA; PLA2G4D; PLA2G3
    Metabolic pathways PAPSS2A; LASS1; PIGW; PGD; ADI1; DPYD; POLG2; PNLIP; KYNU; MCAT
    Ras signaling pathway BRAP; PLA2G10; GRIN2A; BAD; PRKCG; PIK3CB; PIK3R2; PDGFD; FGF2; FGF11
    Vascular smooth muscle contraction GNA12A; CALD1B; CALML5; MAP2K2A; PLA2G6; RAF1A; KCNMB1; PLCB3; CALM4; PLCB4
    Pancreatic secretion CPB2; CLCA2; ATP1A4; GNAS; CELA2A; PLA2G12A; CPA3; BST1; RAC1; TPCN2
    Fat digestion and absorption PLA2G12A; PNLIPRP2; AGPAT2; ABCA1; FABP1; SLC27A4; PLA2G2E; PNLIP; MOGAT3; PNLIPRP1

    PLA2G1B has several biochemical functions, for example, bile acid binding, calcium ion binding, calcium-dependent phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G1B itself. We selected most functions PLA2G1B had, and list some proteins which have the same functions with PLA2G1B. You can find most of the proteins on our site.

    Function Related Protein
    bile acid binding FABP6; PYGL; NR1H4; AKR1C2; PLA2G1B; AKR1C21; FABP1; FABP10A; STARD5
    calcium ion binding PCDHGB6; NKD2A; MATN3; C1RA; S100U; EHD2; CHP2; PCDH19; PCDH2G3; SWAP70B
    calcium-dependent phospholipase A2 activity PLA2G1B; PLA2G4B; PLA2G12A; PLA2G3; PLA2G4F; PLA2G2A; PLA2G5; PLA2G4A
    phospholipase A2 activity PLA2G4A; PLA2G6; ABHD3; PRDX6; PLA2G4AA; PLA2G2F; PLA2G1B; PLA2G2A; PLB1; PLA2G2D
    receptor binding F2; GCG; NSG1; PKD2; ITGA1; INHA; SRC; DAO1; GIPC1; FGF20B

    PLA2G1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G1B here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G1B.


    Karray, A; Ben Ali, Y; et al. Drastic changes in the tissue-specific expression of secreted phospholipases A2 in chicken pulmonary disease. BIOCHIMIE 94:451-460(2012).
    Karray, A; Zarai, Z; et al. Kinetic properties of pancreatic and intestinal sPLA2 from chicken and mammals using the monomolecular film technique. JOURNAL OF COLLOID AND INTERFACE SCIENCE 363:620-625(2011).

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