ppef2
Share
  • Official Full Name
  • protein phosphatase, EF-hand calcium binding domain 2
  • Background
  • This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene.
  • Synonyms
  • PPEF2; protein phosphatase, EF-hand calcium binding domain 2; serine/threonine-protein phosphatase with EF-hands 2; PPP7CB; protein phosphatase 7; catalytic subunit; beta isozyme; protein phosphatase with EF hands 2; protein phosphatase, EF hand calcium-b
Cat.#:PPEF2-13171MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPEF2 Protein
+Inquiry

Protein Function

PPEF2 has several biochemical functions, for example, Hsp70 protein binding, Hsp90 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPEF2 itself. We selected most functions PPEF2 had, and list some proteins which have the same functions with PPEF2. You can find most of the proteins on our site.
Function
Related Protein
Function Hsp70 protein binding
Related Protein BAG6; MVD; PACRG; FAM119A; L7RN6; GPR37; RPS3; TFRC; RNF207; DNAJB2
Function Hsp90 protein binding
Related Protein HDAC6; USP19; NPAS2; STUB1; GBP1; CSNK2A1; PACRG; PPEF2; UNC45B; CHORDC1
Function calcium ion binding
Related Protein NELL2A; EFCAB3; DSG3; F9B; SYTL2; RGN; FAT2; PCLO; MYLPF; BNIP2
Function hydrolase activity
Related Protein FAM108A; ABHD14B; CAPN3B; INPP5J; PRSS52; PRSS41; PPP1CBL; BPGM; NOTUM1B; C1RA
Function iron ion binding
Related Protein CYP46A1.3; AOX1; CYP4A10; ACO2; TYW5; NOS2B; HIF1AN; CYP27A1; CYP3C1L2; CYP20A1
Function manganese ion binding
Related Protein PAPOLA; PPM1AB; PPM1N; IMPA1; PEPD; PPM1BA; PPM1NB; PCK1; ABL2; B4GALT7
Function metal ion binding
Related Protein CYP2K16; ZNF668; PARP12B; ZNF397; PPP6C; NRP2; CD209A; ACSM1; HE1A; GLI2B
Function mitogen-activated protein kinase kinase kinase binding
Related Protein MAP3K11; DUSP19; MAP4K2; MAPK8IP3; MAPK1; PPEF2; MAP2K1; CDC42; CDC37; TRAF2
Function phosphoprotein phosphatase activity
Related Protein PTPN2A; PTPN11B; CTDSPL2A; PPP1CC; PPP3CC; DUSP10; PTPRDB; PPM1LB; PPP3CCB; CTDSPL2B
Function protein serine/threonine phosphatase activity
Related Protein PPP2R5D; PPM1E; UBLCP1; PPP2R2A; PDP1; TAB1; DUSP23; EPM2A; CTDNEP1B; CDC14AA

PPEF2 Related Articles

Dovega, R; Tsutakawa, S; et al. Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A. PLOS ONE 9:-(2014).
Yamaguchi, M; et al. The anti-apoptotic effect of regucalcin is mediated through multisignaling pathways. APOPTOSIS 18:1145-1153(2013).