ppef2
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  • Official Full Name
  • protein phosphatase, EF-hand calcium binding domain 2
  • Background
  • This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene.
  • Synonyms
  • PPEF2; protein phosphatase, EF-hand calcium binding domain 2; serine/threonine-protein phosphatase with EF-hands 2; PPP7CB; protein phosphatase 7; catalytic subunit; beta isozyme; protein phosphatase with EF hands 2; protein phosphatase, EF hand calcium-b
Cat.#:PPEF2-13171MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPEF2 Protein
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Protein Function

PPEF2 has several biochemical functions, for example, Hsp70 protein binding, Hsp90 protein binding, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPEF2 itself. We selected most functions PPEF2 had, and list some proteins which have the same functions with PPEF2. You can find most of the proteins on our site.
Function
Related Protein
Function Hsp70 protein binding
Related Protein PACRG; STUB1; L7RN6; ERN1; BAG6; FAM119A; DNAJB2; MVD; DNAJA1; C11orf73
Function Hsp90 protein binding
Related Protein NPAS2; HDAC6; ERN1; UNC45B; GBP1; CHORDC1; HIF1A; UNC45A; ERBB2; STUB1
Function calcium ion binding
Related Protein PRRG1; CANT1B; NID2; CDH2; Shh; DLK2; HEG; CETN3; RHBDL3; EFEMP2B
Function hydrolase activity
Related Protein INPPL1A; IRGM; CDC14AA; FBP1A; GDPD4; PTPRDB; YDJC; ELA3L; CAPN8; DUSP8A
Function iron ion binding
Related Protein CYP2C18; CYP2AA9; CYP2AA8; CYP1A; CYP21A2; P4HTM; P4HA1A; POR; BRSK2; CYP2X8
Function manganese ion binding
Related Protein PRIMPOL; XPNPEP1; MRE11A; PPM1M; GALNT3; PPM1BA; ATP2C1; DCP2; PAPOLA; WRN
Function metal ion binding
Related Protein TRIM35-19; ZNF697; C1GALT1; ARL3; CHN1; ZNF48; CBFA2T3; TNNC1; CTCFL; DGKD
Function mitogen-activated protein kinase kinase kinase binding
Related Protein CDC42; MAP3K11; MARVELD3; TCF3; MAPK9; STK38; MAPK1; MAPK8IP3; DUSP19; MAP4K2
Function phosphoprotein phosphatase activity
Related Protein PTPN2A; PPP5C; PTPRZ1; PPM1AB; CTDNEP1A; PTPN11B; PPAP2B; MTM1; ACP2; CDC25D
Function protein serine/threonine phosphatase activity
Related Protein CDC14B; PPP3CA; PPM1A; PDP1; CDC14AA; PPM1DA; PPM1L; PPP1R15B; LCK; MTMR4

PPEF2 Related Articles

Dovega, R; Tsutakawa, S; et al. Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A. PLOS ONE 9:-(2014).
Yamaguchi, M; et al. The anti-apoptotic effect of regucalcin is mediated through multisignaling pathways. APOPTOSIS 18:1145-1153(2013).