psma8
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  • Official Full Name
  • proteasome (prosome, macropain) subunit, alpha type, 8
  • Background
  • The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity). This may be a testis-specific subunit.
  • Synonyms
  • PSMA8; proteasome (prosome, macropain) subunit, alpha type, 8; proteasome subunit alpha type-7-like; MGC26605; PSMA7L; Proteasome subunit alpha type 7 like; PSA7L_HUMAN; PSMA 7L; PSMA 8; PSMA8 proteasome (prosome macropain) subunit alpha type 8; PSMA8 proteasome subunit alpha type 8
Cat.#:PSMA8-1320HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 8, His-tagged
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Cat.#:PSMA8-2015HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA8, His-tagged
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Cat.#:PSMA8-30593THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA8, His-tagged
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Cat.#:PSMA8-13568MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PSMA8 Protein
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Cat.#:PSMA8-12382ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PSMA8
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Cat.#:PSMA8-1429HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PSMA8 cell lysate
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Involved Pathway

PSMA8 involved in several pathways and played different roles in them. We selected most pathways PSMA8 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMA8 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
APC/C-mediated degradation of cell cycle proteins
UBE2C; PSMD9; PSMD14; CDK2; AURKB; PSMD5; ANAPC10; PSME3; PSMD10; PSMA8
APC/C:Cdc20 mediated degradation of Securin
PSMD14; PSMD9; PSME3; ANAPC10; UBE2C; PSMD5; PSMD10; PSMA8
APC/C:Cdc20 mediated degradation of mitotic proteins
UBE2C; PSMD9; PSMA8; PSMD14; PSMD10; ANAPC10; PSME3; PSMD5; NEK2
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
PSMD5; AURKB; PSME3; ANAPC10; PSMD14; PSMD10; PSMD9; UBE2C; PSMA8
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
PSME3; PSMD9; PSMA8; UBE2C; NEK2; PSMD10; PSMD5; ANAPC10; PSMD14
ARMS-mediated activation
PSME3; SPRED1; HBEGF; DUSP5; DAB2IPB; PSMD5; DUSP4; CSF2RB; RASGRP1; NETO2
AUF1 (hnRNP D0) binds and destabilizes mRNA
PSMD10; HNRNPD; EIF4G1; PSMD14; PSMD9; PSMD5; PSMA8; PSME3
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
ANAPC10; PSMA8; PSMD14; PSME3; PSMD5; NEK2; UBE2C; PSMD9; PSMD10

Protein Function

PSMA8 has several biochemical functions, for example, endopeptidase activity, threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMA8 itself. We selected most functions PSMA8 had, and list some proteins which have the same functions with PSMA8. You can find most of the proteins on our site.
Function
Related Protein
Function endopeptidase activity
Related Protein RHBDD1; PSMB9; KLK1B3; ECE1; PSMA6; MMP1A; PSMB2; APH1C; KLK1B16; KLK1B11
Function threonine-type endopeptidase activity
Related Protein PSMB3; PSMB4; PSMB2; PSMA8; PSMB9A; PSMA5; PSMA6; PSMB8F; PSMA4; PSMB9