Creative BioMart to Present at IMMUNOLOGY2024™|May 3-7, 2024|Booth #512 Learn More

WASF1

Official Full Name

WAS protein family, member 1
Overview

Wiskott-Aldrich syndrome protein family member 1 is a protein that in humans is encoded by the WASF1 gene.
Synonyms

WASF1; WAS protein family, member 1; wiskott-Aldrich syndrome protein family member 1; KIAA0269; SCAR1; WAVE; WAVE1; protein WAVE-1; WASP family protein member 1; homology of dictyostelium scar 1; verprolin homology domain-containing protein 1; FLJ31482;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	WASF1-368HCL	Recombinant Human WASF1 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	WASF1-18426M	Recombinant Mouse WASF1 Protein	Mammalian Cell	His	Inquiry
Mouse	WASF1-10106M-B	Recombinant Mouse WASF1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	WASF1-10106M	Recombinant Mouse WASF1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	WASF1-6558R	Recombinant Rat WASF1 Protein	Mammalian Cell	His	Inquiry
Rat	WASF1-6214R-B	Recombinant Rat WASF1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	WASF1-6214R	Recombinant Rat WASF1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

WASF1 involved in several pathways and played different roles in them. We selected most pathways WASF1 participated on our site, such as Adherens junction, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with WASF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adherens junction	RHOA;PTBP3;CREBBP;CTNNA2;FGFR1;IGF1RA;PTPN6;CSNK2B;NLK2
Fc gamma R-mediated phagocytosis	ASAP2;SCIN;INPPL1;SPHK2;VAV3;RAF1;PIK3CA;PRKCB;NCF1
Regulation of actin cytoskeleton	RAC3A;IQGAP3;RAC1;CHRM5A;WASL;MLCK2;ITGAX;ITGA9;INSB
Bacterial invasion of epithelial cells	BCAR1;DNM1;CTNNA1;PIK3R5;WAS;RHOA;PIK3R3;PIK3CG;CLTA
Shigellosis	MAPK8;HCLS1;ITGA5;ROCK2;MAPK9;IKBKB;DIAPH1;CD44;PFN1
Salmonella infection	IL8L1;PKN2;ROCK2;PFN2;RAC1;PLEKHM2;TLR4BB;KLC4;PFN4
Choline metabolism in cancer	RALGDS;DGKZ;TSC1;PIK3CA;MAP2K2;GPCPD1;CHKB;RAC2;DGKQ

WASF1 has several biochemical functions, for example, contributes_to Rac GTPase binding, actin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WASF1 itself. We selected most functions WASF1 had, and list some proteins which have the same functions with WASF1. You can find most of the proteins on our site.

Function	Related Protein
contributes_to Rac GTPase binding	BRK1;CYFIP1;NCKAP1;WASF1;ABI2
actin binding	MYO7B;PLS3;KCNMA1;MYBPC2;PARK2;EPB41;Fert2;CLMN;WASF1
protein binding	GATAD2A;ZNF217;HIST1H4I;GLYR1;DNAJC11;DYNLRB1;KRT8;PPP1R2P3;TPR
protein complex binding	CPD;IST1;FBN1;PFKP;KRIT1;SKAP1;PPIB;CDK5RAP2;KAT6B

WASF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WASF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of WASF1.

ABI2; ABL1; TRIP10; PFN1; IFT20; SORBS3; PIK3R1; PFN2

Research Area

Phospholipases, Small GTPases, and Other Molecules in the Akt Pathway

Shi, L; Zhang, LC; et al. Expression, purification and renaturation of truncated human integrin beta 1 from inclusion bodies of Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 107:13-19(2015).

Hu, ZL; Chen, ZY; et al. Expression, purification of IL-38 in Escherichia coli and production of polyclonal antibodies. PROTEIN EXPRESSION AND PURIFICATION 107:76-82(2015).