FGL2
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Official Full Name
fibrinogen-like 2
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Overview
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. -
Synonyms
FGL2; fibrinogen-like 2; fibroleukin; pT49; T49; fibrinogen-like protein 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- CHO
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, targeting FGL2 protein has shown promise in preclinical studies as a potential therapeutic strategy for autoimmune diseases.
FGL2 protein has been implicated in liver fibrosis, cirrhosis, and hepatocellular carcinoma by promoting inflammation, fibrogenesis, and immune dysregulation.
Potential side effects may include immunosuppression, increased risk of infections, and dysregulation of immune homeostasis.
Enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry are commonly used methods for detecting FGL2 protein in clinical samples.
FGL2 protein has been shown to promote cancer cell growth, invasion, and metastasis by modulating immune responses and promoting angiogenesis.
Customer Reviews (3)
Write a reviewBy utilizing the FGL2 protein, I can approach my research with unwavering confidence in its quality, along with the unparalleled support provided by its manufacturer.
Their expertise and prompt responsiveness exemplify their dedication to providing customers with solutions and guidance.
The FGL2 protein offers exceptional quality that seamlessly aligns with my experimental requirements.
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