Active Recombinant Human FGL2 Protein, His-tagged

• Cat.No.: FGL2-01H
• Product Overview: Recombinant Human FGL2 Protein (Asn24-Pro439) with a C-terminal 6-His tag was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 24-439 a.a.
• Description: The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
• Bio-activity: Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated human T cells.
  The ED50 for this effect is 1-8 μg/mL.
• Molecular Mass: 48 kDa
• N-terminal Sequence Analysis: Asp32
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: > 80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: FGL2 fibrinogen like 2 [ Homo sapiens (human) ]
• Official Symbol: FGL2
• Synonyms: FGL2; fibrinogen like 2; T49; pT49; fibroleukin; fibrinogen-like protein 2
• Gene ID: 10875
• mRNA Refseq: NM_006682
• Protein Refseq: NP_006673
• MIM: 605351
• UniProt ID: Q14314