RAC3
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Official Full Name
Rac-like GTP-binding protein ARAC3
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Overview
A member of ROP GTPase gene family; Encodes a Rho-like GTP binding protein. -
Synonyms
RAC3; Rac-like GTP-binding protein ARAC3; ARAC3; ATROP6; GTPase protein ROP6; Rac like GTP binding protein ARAC3; Rho related protein from plants 6; RHO1PS; ROP6; RAC-like 3 (RAC3); FUNCTIONS IN: GTP binding, GTPase activity; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: in 6 components; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras small GTPase, Rab type (InterPro:IPR003579), Ras (InterPro:IPR013753), Ras small GTPase, Ras type (InterPro:IPR003577), Small GTPase, Rho type (InterPro:IPR003578); BEST Arabidopsis thaliana protein match is: RAC-like GTP binding protein 5 (TAIR:AT1G75840.1).; M4E13.80; M4E13_80; RAC-like 3; RHO-RELATED PROTEIN FROM PLANTS 6;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- RAC3 Related Research Area
- RAC3 Related Signal Pathway
RAC3 involved in several pathways and played different roles in them. We selected most pathways RAC3 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | JUND;BRAF;PPM1AB;STK4;RAP1B;FAS;NFATC1;PLA2G4AA;HSPA8 |
| Ras signaling pathway | GNG13;PRKCA;RALBP1;GNG3;RASA4;PRKACB;RGL1;KITLG;RAC2 |
| Rap signaling pathway | FGF21;ARAP3;FGF8;PIK3CA;MAPK1;FGFR4;Itgam&Itgb2;PDGFB;PDGFD |
| cAMP signaling pathway | MLLT4;CNGA4;ROCK2;AKT1;RAP1B;HTR1B;CREB3L3;GRIN2C;CREB3L1 |
| Sphingolipid signaling pathway | PIK3CA;PLCB4;MAP3K5;PPP2R5D;LASS5;MAPK13;MS4A2;S1PR5;SGMS2 |
| Wnt signaling pathway | CER1;WNT11;TRP53;PRKACAA;MAPK9;NFATC3;WNT4;DVL1B;SIAH1 |
| Axon guidance | FGF20A;KIF4A;Ntng2;GNAI3;MYL12A;JAK2;CLTB;SCN4A;AKAP9 |
| VEGF signaling pathway | CDC42L2;PRKCBB;PIK3R2;PRKCB;CDC42;SPHK2;MAPK1;PTGS2A;SH2D2A |
| Focal adhesion | IGF1;ITGA1;PRKCB;ROCK2A;COL27A1B;ITGA7;ITGB8;PIK3R1;Pdgfa&Pdgfb |
| Adherens junction | INSRA;ACTN2;SMAD3A;SRC;TGFBR2;BAIAP2;MET;EGFRA;RHOAB |
| Natural killer cell mediated cytotoxicity | SHC4;KIR3DL2;ZAP70;PTPN6;VAV3;RAET1D;PPP3CA;LCK;BRAF |
| B cell receptor signaling pathway | NFKB1;PIK3AP1;CTNNB2;VAV3;SLA2;RAC2;NEDD9;FOS;PDPK1A |
| Fc epsilon RI signaling pathway | RAC2;MAP2K4;VAV3;MAPK9;MAPK12;PLA2G4D;GRB2;MAP2K3;SYK |
| Regulation of actin cytoskeleton | RAC1;DIAP1;FGF20;GNA13A;ARHGAP35;IQGAP3;DIAPH3;NRAS;FGF12 |
| Pathways in cancer | APPL1;FLT3;F2R;CASP9;LPAR3;FZD6;FOS;GNAI1;TGFA |
| Colorectal cancer | PIK3CD;CCND1;MAPK9;MAPK1;RALGDS;SMAD2;PIK3R2;GSK3B;BCL2 |
| Pancreatic cancer | TGFB2;MAPK1;BCL2L1;IKBKG;MAPK8;SMAD2;BAD;TGFBR2;KRAS |
| Choline metabolism in cancer | MAP2K2;RAC3;PIP5K1A;MTOR;EIF4EBP1;PLA2G4C;CHKA;DGKG;PRKCB |
| Viral myocarditis | CD40;ICAM1;HLA-DQA1;CD40LG;SGCG;ITGAL;PRF1;SGCB;MYH7 |
RAC3 has several biochemical functions, for example, GTP binding, GTPase activity, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RAC3 itself. We selected most functions RAC3 had, and list some proteins which have the same functions with RAC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | RHOAD;NUDT2;RAP1B;ARL1;LANCL2;TUBA3D;RAB3AB;SEPT6;RAB41 |
| GTPase activity | RHOB;RAB39A;GNAI3;GNG5;MFN1;SEPT5;GNA15;RAB24;TUBB1 |
| calcium-dependent protein binding | SYN1;S100A1;S100A6;DDX5;S100B;VPS37B;SNAP25;SELP;C9orf9 |
| protein binding | CAPNS1;CNTF;NR2F1;PYCRL;GIMAP5;MAGEH1;SERPINB5;KHDC3;IER3 |
RAC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RAC3.
ESR1; NRBP1; XIAP; LDHB; NEFM; NCL; HIVEP2; WAS; NAP1L1; PAK1; DDX46; RBM41; RSRC1; RWDD1
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