Description : |
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. |
Source : |
Mammalian cells |
Species : |
Human |
Tag : |
Flag |
Form : |
25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : |
21.2 kDa |
AA Sequence : |
MQAIKCVVVGDGAVGKTCLLISYTT NAFPGEYIPTVFDNYSANVMVDGKP VNLGLWDTAGQEDYDRLRPL SYPQTDVFLICFSLVSPASFENVRA KWYPEVRHHCPHTPILLVGTKLDLR DDKDTIERLRDKKLAPITYP QGLAMAREIGSVKYLECSALTQRGL KTVFDEAIRAVLCPPPVKKPGKKCT VFTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : |
Store at -80 centigrade. |
Concentration : |
>50 ug/mL as determined by microplate BCA method. |
Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : |
Druggable Genome |
Protein Pathways : |
Adherens junction, Axon guidance, B cell receptor signaling pathway, Colorectal cancer, Fc epsilon RI signaling pathway, Focal adhesion, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Pancreatic cancer, Pathways in cancer, Regulation of actin cytoskeleton, VEGF signaling pathway, Viral myocarditis, Wnt signaling pathway |