dpep2
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  • Official Full Name
  • dipeptidase 2
  • Background
  • DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides,;including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed;during glutathione degradation (Habib et al., 2003 (PubMed 12738806)).
  • Synonyms
  • DPEP2; dipeptidase 2; Dipeptidase2; DPEP 2; MBD 2; MBD2
Cat.#:DPEP2-208HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPEP2 Protein, His-tagged
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Cat.#:DPEP2-2824HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DPEP2 Protein, GST-tagged
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Cat.#:DPEP2-12137HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DPEP2, GST-tagged
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Cat.#:DPEP2-8610HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPEP2, Fc tagged
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Cat.#:DPEP2-8611HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPEP2, His tagged
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Cat.#:DPEP2-4780MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DPEP2 Protein
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Cat.#:DPEP2-1937RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DPEP2 Protein
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Cat.#:DPEP2-1162HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPEP2 cell lysate
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Cat.#:DPEP2-1177HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human DPEP2 cell lysate
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Involved Pathway

DPEP2 involved in several pathways and played different roles in them. We selected most pathways DPEP2 participated on our site, such as Aflatoxin activation and detoxification, Arachidonic acid metabolism, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPEP2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aflatoxin activation and detoxification
FAM84B; DPEP2; CYP3A4; DPEP1; ACY3.1; CYP1A2; GGTLC1; CYP2A13; GGT6; PRKRA
Arachidonic acid metabolism
CYP2C39; GGT1; CYP2J2; CYP2J5; ALOX5AP; PLA2G2F; AWAT1; CYP4F22; CBR2; CYP2AD3
Biological oxidations
Sult2a2; AADAC; CYP3A7-CYP3AP1; CYP19A1; CYP2C18; CYP2S1; PRKRA; ACSM1; CYP2B6; FDX1
Metabolism
CYGB1; FABP11B; ATP5S; GLIPR1; SURF1; AGPAT6; CYP2AD2; MTF1; ARL2BP; CYP3C1
Metabolism of lipids and lipoproteins
APOEA; PHOSPHO1; ARSI; MTF1; GC; CEPT1; MED9; CDK19; MED19; ARSK
Synthesis of Leukotrienes (LT) and Eoxins (EX)
ALOX5AP; ALOX5B.3; PTGR1; ALOX5B.2; DPEP2; DPEP1
leukotriene biosynthesis
DPEP1; DPEP2

Protein Function

DPEP2 has several biochemical functions, for example, dipeptidase activity, dipeptidyl-peptidase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPEP2 itself. We selected most functions DPEP2 had, and list some proteins which have the same functions with DPEP2. You can find most of the proteins on our site.
Function
Related Protein
Function dipeptidase activity
Related Protein PEPD; NAALADL1; SCRN1; SCRN3; DPEP3; NAALAD2; FOLH1; DPEP2; SCRN2; CNDP1
Function dipeptidyl-peptidase activity
Related Protein DPP7; DPEP3; DPEP2; DPP4; DPP8; FAP; DPP3; NAALAD2; DPEP1; PRCP
Function metal ion binding
Related Protein ADH8A; POLH; ATP9B; PRKCI; ATP13A4; NT5C2B; TRAF4B; ZSCAN4D; ATF2; ZNF821
Function metalloexopeptidase activity
Related Protein ERAP1; RNPEP; METAP1; NPEPL1; METAP2; DPEP2; DPEP1; DPEP3; NUDT16; METAP2A

Interacting Protein

DPEP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPEP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPEP2.
uvrA

DPEP2 Related Articles

Sabra, A; Bessoule, JJ; et al. Host-Pathogen Interaction and Signaling Molecule Secretion Are Modified in the dpp3 Knockout Mutant of Candida lusitaniae. INFECTION AND IMMUNITY 82:413-422(2014).
Hast, BE; Goldfarb, D; et al. Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination. CANCER RESEARCH 73:2199-2210(2013).