Recombinant Human DPEP2 Protein (Leu303-Leu486), His tagged

• Cat.No.: DPEP2-2205H
• Product Overview: Recombinant human DPEP2 (Leu303-Leu486) fused with His tag was expressed in E. coli.

Specification

• Description: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1), membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3). MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen. MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4). It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 21.46 kDa
• Protein Length: Leu303-Leu486
• Purity: >90% as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: DPEP2 dipeptidase 2 [ Homo sapiens (human) ]
• Official Symbol: DPEP2
• Synonyms: DPEP2; dipeptidase 2; MBD2
• Gene ID: 64174
• mRNA Refseq: NM_022355
• Protein Refseq: NP_071750
• MIM: 609925
• UniProt ID: Q9H4A9