mfap5
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  • Official Full Name
  • microfibrillar associated protein 5
  • Background
  • This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2.
  • Synonyms
  • MFAP5; microfibrillar associated protein 5; microfibrillar-associated protein 5; MAGP2; MP25; MAGP 2; MAGP-2; MFAP 5; MFAP-5; MFAP5_HUMAN; Microfibril associated glycoprotein 2; Microfibril-associated glycoprotein 2; Microfibrillar associated protein 5 precursor; microfibril-associated glycoprotein-2
Cat.#:MFAP5-1243HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MFAP5 Protein, MYC/DDK-tagged
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Cat.#:MFAP5-290HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MFAP5 Protein, His-tagged
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Cat.#:MFAP5-4387HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MFAP5 Protein, GST-tagged
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Cat.#:Mfap5-291MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mfap5 Protein, His-tagged
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Cat.#:Mfap5-292RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mfap5 Protein, His-tagged
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Cat.#:MFAP5-5689HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human Microfibrillar Associated Protein 5, His-tagged
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Cat.#:MFAP5-8554HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MFAP5, His tagged
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Cat.#:Mfap5-316MTag:His
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse Mfap5, His-tagged
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Cat.#:MFAP5-9780MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MFAP5 Protein
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Cat.#:MFAP5-1395HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human MFAP5 cell lysate
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Involved Pathway

MFAP5 involved in several pathways and played different roles in them. We selected most pathways MFAP5 participated on our site, such as Elastic fibre formation, Extracellular matrix organization, Molecules associated with elastic fibres, which may be useful for your reference. Also, other proteins which involved in the same pathway with MFAP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Elastic fibre formation
ABHD1; ITGB3A; LTBP2; FBN1; MFAP1B; MFAP3; EFEMP2; MFAP1; FURINB; LTBP3
Extracellular matrix organization
MMP8; MMP10; LOXL1; ITGB3A; FAM49BA; LOXL4; MATN3; MMP17; PPIB; COL28A1A
Molecules associated with elastic fibres
MFAP4; FBLN2; MFAP5; LTBP2; MFAP1B; EFEMP1; EFEMP2; MFAP1; FBLN1; LTBP4
Notch signaling pathway
LNX1; DVL1B; PTCRA; TLE3A; DTX4; RBPJB; MIB1; KAT2A; MFNG; JAG1A

Protein Function

MFAP5 has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by MFAP5 itself. We selected most functions MFAP5 had, and list some proteins which have the same functions with MFAP5. You can find most of the proteins on our site.
Function
Related Protein
Function extracellular matrix structural constituent
Related Protein COL4A1; COL24A1; COL1A1A; MGP; ELNA; ELN; KAL1; COL1A2; COL4A6; COL8A2

MFAP5 Related Articles

Saekmose, SG; Schlosser, A; et al. Enzyme-Linked Immunosorbent Assay Characterization of Basal Variation and Heritability of Systemic Microfibrillar-Associated Protein 4. PLOS ONE 8:-(2013).
Akhtar, S; Davies, JR; et al. Ultrastructural immunolocalization of alpha-elastin and keratan sulfate proteoglycan in normal and scoliotic lumbar disc. SPINE 30:1762-1769(2005).