CLPP
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Official Full Name
ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog
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Overview
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. -
Synonyms
CLPP; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli); ClpP (caseinolytic protease, ATP dependent, proteolytic subunit, E. coli) homolog , ClpP caseinolytic protease, ATP dependent, proteolytic subunit homolog (E. coli);
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bacillus subtilis
- Clostridium Botulinum
- E.coli
- Human
- Mouse
- Staphylococcus
- Streptomyces coelicolor A3(2)
- Zebrafish
- E. coli or Yeast
- E.coli
- HEK293
- HEK293T
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- His|SUMO
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- CLPP Related Articles
CLPP involved in several pathways and played different roles in them. We selected most pathways CLPP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CLPP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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CLPP has several biochemical functions, for example, identical protein binding, peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLPP itself. We selected most functions CLPP had, and list some proteins which have the same functions with CLPP. You can find most of the proteins on our site.
Function | Related Protein |
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identical protein binding | CLDN8;CEACAM5;TRIP13;EPOR;VAMP2;DIAP1;SYNE1;SDK2;TNK2 |
peptidase activity | HTRA1B;BACE1;TMPRSS13A;GZMF;ELANE;MMP14B;DESI1;IHH;METAP2 |
protein binding | ASCL1;G3BP2;PSMC2;ANKRD49;ZNF263;BOP1;STAU2;FBXO11;MAP4K3 |
serine-type endopeptidase activity | PRSS58;PCSK4;CTRC;PREP;LTF;TMPRSS11D;TYSND1;KLK1B9;ELA2L |
CLPP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLPP here. Most of them are supplied by our site. Hope this information will be useful for your research of CLPP.
SAP18; GH1; HLA-B; C20orf24; NDUFA4; IDH3B; CS; PMPCB; MTRF1; CLPX; CDS2; MT-ND1; MT-ATP8; FDX1; COX5B; ACADM; COX6A1; ALAS1; COX7C; COX5A
- Q&As
- Reviews
Q&As (7)
Ask a questionTargeting CLPP therapeutically could offer potential in diseases related to mitochondrial dysfunction and aging.
CLPP activity is tightly regulated to ensure balanced protein turnover in mitochondria.
Dysregulation of CLPP is linked to various diseases, including mitochondrial disorders.
It helps in degrading misfolded or damaged proteins, maintaining mitochondrial function.
Proper functioning of CLPP is vital for mitochondrial health and energy production.
CLPP levels and activity are associated with aging, influencing cellular senescence and longevity.
CLPP plays a crucial role in mitochondrial protein degradation and quality control.
Customer Reviews (3)
Write a reviewVery high purity level.
Worked excellently in experiments.
Product was well packaged.
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