Recombinant Mouse Clpp Protein, Myc/DDK-tagged

• Cat.No.: Clpp-2197M
• Product Overview: Purified recombinant protein of mouse full-length caseinolytic mitochondrial matrix peptidase proteolytic subunit (Clpp), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 29.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit [ Mus musculus (house mouse) ]
• Official Symbol: Clpp
• Synonyms: CLPP; caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli); putative ATP-dependent Clp protease proteolytic subunit, mitochondrial; endopeptidase Clp; caseinolytic protease, ATP-dependent, proteolytic subunit homolog; AU019820; D17Wsu160e
• Gene ID: 53895
• mRNA Refseq: NM_017393
• Protein Refseq: NP_059089
• UniProt ID: O88696