fgg
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  • Official Full Name
  • fibrinogen gamma chain
  • Background
  • The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three;pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin;which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin;regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several;cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and;thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
  • Synonyms
  • FGG; fibrinogen gamma chain; fibrinogen, gamma polypeptide
Cat.#:FGG-378HTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human FGG Protein
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Cat.#:FGG-884MTag:
Source (Host):YeastSpecies:Mouse
Product nameRecombinant Mouse FGG Protein (Val168-Val436)
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Cat.#:FGG-2239HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGG Protein, MYC/DDK-tagged
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Cat.#:FGG-4150HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FGG Protein, GST-tagged
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Cat.#:FGG-731HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGG Protein, His-tagged
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Cat.#:Fgg-732MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgg Protein, His-tagged
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Cat.#:Fgg-733RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fgg Protein, His-tagged
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Cat.#:FGG-729BTag:His
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine FGG Protein, His-tagged
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Cat.#:FGG-730CTag:His
Source (Host):E. coliSpecies:Chicken
Product nameRecombinant Chicken FGG Protein, His-tagged
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Cat.#:FGG-103HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FGG, His-tagged
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Cat.#:FGG-12884HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGG, His-tagged
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Cat.#:FGG-438HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human FGG protein, His-tagged
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Cat.#:FGG-2342RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FGG Protein
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Cat.#:FGG-6547CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FGG
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Cat.#:FGG-12289ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FGG
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Cat.#:FGG-7HTag:N/A
Source (Host):Species:Human
Product nameNative Human Fibrinogen, FITC Labeled
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Cat.#:Fgg -65RTag:N/A
Source (Host):Species:Rat
Product nameNative Rat Fibrinogen, FITC Labeled
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Cat.#:Fgg -69RTag:N/A
Source (Host):Species:Rat
Product nameNative Rat Fibrinogen
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Cat.#:Fgg-5421RTag:N/A
Source (Host):Rat plasmaSpecies:Rat
Product nameNative Rat Fibrinogen Gamma Chain
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Cat.#:FGG -36DTag:N/A
Source (Host):Species:Dog
Product nameNative Canine Fibrinogen
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Cat.#:FGG -44DTag:N/A
Source (Host):Species:Dog
Product nameNative Canine Fibrinogen, FITC Labeled
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Cat.#:FGG -32BTag:N/A
Source (Host):Species:Bovine
Product nameNative Bovine Fibrinogen
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Cat.#:FGG -41BTag:N/A
Source (Host):Species:Bovine
Product nameNative Bovin Fibrinogen, FITC Labeled
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Cat.#:FGG -57RTag:N/A
Source (Host):Species:Rabbit
Product nameNative Rabbit Fibrinogen, FITC Labeled
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Cat.#:FGG -60RTag:N/A
Source (Host):Species:Rabbit
Product nameNative Rabbit Fibrinogen
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Cat.#:FGG -47PTag:N/A
Source (Host):Species:Pig
Product nameNative Porcine Fibrinogen, FITC Labeled
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Cat.#:FGG -48STag:N/A
Source (Host):Species:Sheep
Product nameNative Sheep Fibrinogen, FITC Labeled
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Cat.#:FGG-53STag:N/A
Source (Host):Species:Sheep
Product nameNative Sheep Fibrinogen
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Cat.#:FGG-6231HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FGG 293 Cell Lysate
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Involved Pathway

FGG involved in several pathways and played different roles in them. We selected most pathways FGG participated on our site, such as Complement and coagulation cascades, Platelet activation, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Complement and coagulation cascades
C1R; GM5077; F13A1; C3; PLAT; CFD; SERPINA1D; C7; CD59A; C2
Platelet activation
FCGR2A; FGA; PIK3R3; TBXAS1; PLCB2; PLCB3; VWF; ACTB; PTGS1; VASP
Staphylococcus aureus infection
CFB; C4A; SELPLG; ITGB2; HLA-DPA1; FGG; H2-AB1; FCGR2C; CFI; FPR3

Protein Function

FGG has several biochemical functions, for example, cell adhesion molecule binding, metal ion binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by FGG itself. We selected most functions FGG had, and list some proteins which have the same functions with FGG. You can find most of the proteins on our site.
Function
Related Protein
Function cell adhesion molecule binding
Related Protein PVRL3; NCR3; NPTN; NRXN2; CPE; FGFR1; PVRL3B; NLGN4X; AMICA1; TENM2
Function metal ion binding
Related Protein PPM1BA; B3GAT2; ACAN; ZZEF1; PDE6B; CYB5D1; CYP2B19; FCNA; RNF187; NRXN2A
Function protein binding, bridging
Related Protein RAD50; SPRR1B; GOLGA5; RBM14; VPS18; SYNM; TJP2; EVPL; CNTLN; NEFL
Function receptor binding
Related Protein CD70; MTSS1; FGF1A; BLK; RND1; AGRP2; GSDMA2; CCL15; TESPA1; CNTFR
Function structural molecule activity
Related Protein CDC42SE2; MAP7; COL15A1B; PRPH; KRT9; MAP7D2A; CLDN5B; TUBGCP3; EIF3A; TUBG2

Interacting Protein

FGG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGG here. Most of them are supplied by our site. Hope this information will be useful for your research of FGG.
FGA; ICAM1; q9wmx2-pro_0000037550; d-mannose

FGG Related Articles

You, QM; Verschoor, CP; et al. Proteomic analysis of plasma from Holstein cows testing positive for mycobacterium avium subsp Paratuberculosis (MAP). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 148:243-251(2012).
Kaiser, R; Li, YH; et al. Genetic Risk Factors for Thrombosis in Systemic Lupus Erythematosus. JOURNAL OF RHEUMATOLOGY 39:1603-1610(2012).