Recombinant Human FGG Protein, His-tagged

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Recombinant Human FGG Protein, His-tagged

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Cat.No. : FGG-731H
Product Overview : Recombinant Human FGG(Lys166~Asn416) fused with His tag at N-terminal was expressed in E. coli.
Description : The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 29.9kDa
Protein length : Lys166~Asn416
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : FGG fibrinogen gamma chain [ Homo sapiens ]
Official Symbol : FGG
Synonyms : FGG; fibrinogen gamma chain; fibrinogen, gamma polypeptide;
Gene ID : 2266
mRNA Refseq : NM_000509
Protein Refseq : NP_000500
MIM : 134850
UniProt ID : P02679

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