Recombinant Human FGG Protein, GST-tagged
Cat.No. : | FGG-4150H |
Product Overview : | Human FGG full-length ORF (BAF82111.1, 1 a.a. - 453 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 77.9 kDa |
AA Sequence : | MSWSLHPRNLILYFYALLFLSSTCV AYVATRDNCCILDERFGSYCPTTCG IADFLSTYQTKVDKDLQSLEDILHQ VENKTSEVKQLIKAIQLTYNPDESS KPNMIDAATLKSRKMLEEIMKYEAS ILTHDSSIRYLQEIYNSNNQKIVNL KEKVAQLEAQCQEPCKDTVQIHDIT GKDCQDIANKGAKQSGLYFIKPLKA NQQFLVYCEIDGSGNGWTVFQKRLD GSVDFKKNWIQYKEGFGHLSPTGTT EFWLGNEKIHLISTQSAIPYALRVE LEDWNGRTSTADYAMFKVGPEADKY RLTYAYFAGGDAGDAFDGFDFGDDP SDKFFTSHNGMQFSTWDNDNDKFEG NCAEQDGSGWWMNKCHAGHLNGVYY QGGTYSKASTPNGYDNGIIWATWKT RWYSMKKTTMKIIPFNRLTIGEGQQ HHLGGAKQVRPEHPAETEYDSLYPE DDL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FGG fibrinogen gamma chain [ Homo sapiens ] |
Official Symbol : | FGG |
Synonyms : | FGG; fibrinogen gamma chain; fibrinogen, gamma polypeptide; |
Gene ID : | 2266 |
mRNA Refseq : | NM_000509 |
Protein Refseq : | NP_000500 |
MIM : | 134850 |
UniProt ID : | P02679 |
Products Types
◆ Recombinant Protein | ||
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FGG-1998R | Recombinant Rat FGG Protein, His (Fc)-Avi-tagged | +Inquiry |
FGG-884M | Recombinant Mouse FGG Protein (Val168-Val436) | +Inquiry |
Fgg-732M | Recombinant Mouse Fgg Protein, His-tagged | +Inquiry |
FGG-427H | Recombinant Human FGG Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Native Protein | ||
FGG-7H | Native Human Fibrinogen, FITC Labeled | +Inquiry |
FGG -41B | Native Bovin Fibrinogen, FITC Labeled | +Inquiry |
FGG -60R | Native Rabbit Fibrinogen | +Inquiry |
◆ Lysates | ||
FGG-6231HCL | Recombinant Human FGG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionInflammatory stimuli and cytokines can modulate FGG gene expression, influencing the synthesis of fibrinogen gamma chain during inflammatory responses.
The FGG gamma chain, along with alpha and beta chains, contributes to the polymerization of fibrin by forming intermolecular bonds between fibrin molecules.
Fibrinogen is a crucial factor in blood coagulation, as it is converted to fibrin during the final stages of the coagulation cascade, forming a stable blood clot.
Fibrinogen (FGG), converted to fibrin, forms the matrix for blood clotting at wound sites, facilitating tissue repair and providing a scaffold for cell migration.
The FGG gene is transcribed in hepatocytes, and the resulting mRNA is translated into the fibrinogen gamma chain during the synthesis of fibrinogen.
Customer Reviews (3)
Write a reviewThis product consistently delivers accurate results in our experiments.
Ordered, and this product was in our hands sooner than expected, facilitating our research timeline.
Quick service! The team provided efficient assistance in choosing the right protein for us.
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