Recombinant Full Length Human FGG Protein, GST-tagged

• Cat.No.: FGG-4930HF
• Product Overview: Human FGG full-length ORF (BAF82111.1, 1 a.a. - 453 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 77.9 kDa
• Protein Length: 453 amino acids
• AA Sequence: MSWSLHPRNLILYFYALLFLSSTCV AYVATRDNCCILDERFGSYCPTTCG IADFLSTYQTKVDKDLQSLEDILHQ VENKTSEVKQLIKAIQLTYNPDESS KPNMIDAATLKSRKMLEEIMKYEAS ILTHDSSIRYLQEIYNSNNQKIVNL KEKVAQLEAQCQEPCKDTVQIHDIT GKDCQDIANKGAKQSGLYFIKPLKA NQQFLVYCEIDGSGNGWTVFQKRLD GSVDFKKNWIQYKEGFGHLSPTGTT EFWLGNEKIHLISTQSAIPYALRVE LEDWNGRTSTADYAMFKVGPEADKY RLTYAYFAGGDAGDAFDGFDFGDDP SDKFFTSHNGMQFSTWDNDNDKFEG NCAEQDGSGWWMNKCHAGHLNGVYY QGGTYSKASTPNGYDNGIIWATWKT RWYSMKKTTMKIIPFNRLTIGEGQQ HHLGGAKQVRPEHPAETEYDSLYPE DDL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FGG fibrinogen gamma chain [ Homo sapiens ]
• Official Symbol: FGG
• Synonyms: FGG; fibrinogen gamma chain; fibrinogen, gamma polypeptide
• Gene ID: 2266
• mRNA Refseq: NM_000509
• Protein Refseq: NP_000500
• MIM: 134850
• UniProt ID: P02679