gng12
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  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma 12
  • Synonyms
  • GNG12; guanine nucleotide binding protein (G protein), gamma 12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; G-protein gamma-12 subunit; Guanine nucleotide binding protein (G protein) gamma 12; Hypothetical protein DKFZp762E193; OTTHUMP00000011139
Cat.#:GNG12-5066HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNG12 Protein, GST-tagged
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Cat.#:GNG12-7034MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GNG12 Protein
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Cat.#:GNG12-1902RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GNG12 Protein, His-tagged
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Cat.#:GNG12-5855HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GNG12 293 Cell Lysate
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Involved Pathway

GNG12 involved in several pathways and played different roles in them. We selected most pathways GNG12 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
CACNA2D4; TGFB1; FGF5; FGF2; RPS6KA2; PRKACBB; FAS; FGF9; CDC42L; PPP3CCA
Ras signaling pathway
HGF; PLCG2; NRAS; FGF5; GRIN2A; RALGDS; KITLG; BRAP; PDGFD; GNG5
Chemokine signaling pathway
HRAS; VAV3; CCL14; CX3CR1; GNB4; RLN1; PTK2B; CXCR6; CCR1; PIK3R5
PIK-Akt signaling pathway
GNB2; TNXB; GNB4; IKBKG; FGF6; TCL1B; FASLG; RXRA; PRLR; FGF5
Circadian entrainment
Adcy4; GRIN2A; GNAQ; PER1; GNAO1; GNG12; ITPR3; GNB4; GNG13; KCNJ5
Retrograde endocannabinoid signaling
NAPEPLD; GNAI1; MAPK9; GABRA1; GABRE; ABHD6; SLC17A8; GABRB3; GNG10; GRIA4
Glutamatergic synapse
GNB1; GRIK1; GNAI2; HOMER1; PRKACG; PRKCB; PRKACB; GNAI1; GRM4; SLC17A6
Cholinergic synapse
CAMK2B; CHRM5; GNG4; NRAS; GNG11; PIK3CD; CREB3L2; ACHE; CHRM1; MAPK1
Serotonergic synapse
HTR3C; CYP2C55; TPH2; CYP2J5; Casp3; ALOX15; ALOX5; GNB4; PLA2G4F; HTR3E
GABAergic synapse
GABRA5; GNG4; GPHN; SLC12A5; SLC6A1; SLC6A13; GABARAPL2; GNB4; GNGT1; GNAO1
Dopaminergic synapse
KCNJ6; GRIA1; MAPK8; MAPK12; MAOB; PLCB1; PPP1CB; GNAI3; GNG13; MAPK10
Regulation of actin cytoskeleton
MSNA; MOS; ROCK1; WAS; RAC1; RAF1B; GNG12A; PDGFC; RRAS2; ITGAL
Morphine addiction
GABRB2; PDE7B; ARRB1; GABRA6; GABRP; GNG11; GNG3; GABRR2; PRKCB; Adcy4
Alcoholism
GNG3; HIST1H2BB; HIST1H2AM; DDC; HIST1H2AN; GM14483; HIST2H3A; HAT1; HIST1H4K; H3F3C
Pathways in cancer
RAC2; FGFR1; WNT1; FLT3; CXCL12; HGF; MMP9; CTNNA3; PTCH1; PDGFRB

Protein Function

GNG12 has several biochemical functions, for example, PDZ domain binding, phosphate ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG12 itself. We selected most functions GNG12 had, and list some proteins which have the same functions with GNG12. You can find most of the proteins on our site.
Function
Related Protein
Function PDZ domain binding
Related Protein SNTA1; GNG12; ATP2B2; CFTR; Fzd4; DOCK4; SSTR2; PLEKHA2; CRIPT; KCNJ4
Function phosphate ion binding
Related Protein ADSSL1; OTC; ADSS; CHST14; SLC34A2; RELA; SH2B3; PNP; MTHFD2; G6PC
Function protein binding
Related Protein C14orf135; RNF220; PLA2G16; ZHX3; INPP5B; ASF1A; GLRA1; DTNA; INTS9; DDX21
Function signal transducer activity
Related Protein ADRB2A; GNB2; TRIM55; ERG; OLFR493; FAM126A; OLFR24; OPN4.1; GNAI2A; PLCD4

Interacting Protein

GNG12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG12 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG12.
FHL2; Cbx1; EIF4A2; Trim69; Poc1b; Mau2; RIPK3; FLNA; MYH9; Bmpr1a; BLK; Gnb1; Myh10; Kctd5; Ppp2r2d

GNG12 Related Articles

Babadagli, ME; Tezcan, B; et al. Matrilin-3 as a putative effector of C-type natriuretic peptide signaling during TGF-beta induced chondrogenic differentiation of mesenchymal stem cells. MOLECULAR BIOLOGY REPORTS 41:5549-5555(2014).
Harlid, S; Xu, ZL; et al. CpG Sites Associated with Cigarette Smoking: Analysis of Epigenome-Wide Data from the Sister Study. ENVIRONMENTAL HEALTH PERSPECTIVES 122:673-678(2014).