ppif
Share
  • Official Full Name
  • Peptidylprolyl Isomerase F
  • Background
  • The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
  • Synonyms
  • PPIF; CYP3; Cyp-D; peptidyl-prolyl cis-trans isomerase F, mito-chondrial; PPIase F; rotamase F; cyclophilin 3; cyclophilin D; cyclophilin F; FLJ90798; MGC117207; OTTHUMP00000019925; OTTHUMP00000019926; peptidyl-prolyl cis-trans isomerase, mitochondrial; EC 5.2.1.8; peptidylprolyl isomerase F (cyclophilin F); hCyP3; peptidylprolyl isomerase F
Cat.#:PPIF-1101HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase F, His-tagged
+Inquiry
Cat.#:PPIF-1429HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase F, His-tagged
+Inquiry
Cat.#:PPIF-120HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl isomerase F
+Inquiry
Cat.#:PPIF-159HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIF protein, T7-tagged
+Inquiry
Cat.#:PPIF-27049THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIF
+Inquiry
Cat.#:PPIF-631HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PPIF Protein, His-tagged
+Inquiry
Cat.#:PPIF-817HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase F, T7-tagged
+Inquiry
Cat.#:PPIF-13184MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPIF Protein
+Inquiry
Cat.#:Ppif-7103MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ppif protein, His-tagged
+Inquiry
Cat.#:Ppif-109RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ppif, His-tagged
+Inquiry
Cat.#:PPIF-4603RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPIF Protein
+Inquiry
Cat.#:PPIF-3547RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPIF Protein, His-tagged
+Inquiry
Cat.#:PPIF-2888CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPIF
+Inquiry
Cat.#:PPIF-2970HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPIF 293 Cell Lysate
+Inquiry

Involved Pathway

PPIF involved in several pathways and played different roles in them. We selected most pathways PPIF participated on our site, such as Calcium signaling pathway, Huntingtons disease, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
PTGER1A; PPP3CCA; SLC8A3; RYR1; PLCB4; VDAC3; NOS2; TRHRB; ADRB3A; GNA14
Huntingtons disease
SLC25A4; NDUFV3; NDUFC1; DNAH11; NDUFB8; VDAC3; COX5A; NDUFA10; COX7A2; ITPR1
Parkinsons disease
UQCRH; NDUFB4; PARK7; NDUFA13; SDHC; MT-ND4; UBA1; PINK1; SDHA; NDUFA4L2
Toxoplasmosis
HLA-DQA2; GNAI3; NOS2; HLA-DMB; ITGB1; IL12A; MAPK8; HLA-DRB4; CD40; CASP9
cGMP-PKG signaling pathway
BAD; PRKG2; VASP; ITPR1; ROCK2; CALM1; MEF2C; PPP1CA; ATP1B4; FXYD2

Protein Function

PPIF has several biochemical functions, for example, cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIF itself. We selected most functions PPIF had, and list some proteins which have the same functions with PPIF. You can find most of the proteins on our site.
Function
Related Protein
Function cyclosporin A binding
Related Protein PPID; PPIC; PPIH; PPIE; PPIG; PPIF
Function peptidyl-prolyl cis-trans isomerase activity
Related Protein PPIG; PPIL2; PPIL4; PPIL3; RANBP2; PPIAA; PPIL6; PIN4; FKBP4; FKBP10
Function protein binding
Related Protein MRAP2; SH2B2; ABCG8; CHPF; JAG1; CUL4B; ANXA7; NME4; EIF4E2; DNMT3L

Interacting Protein

PPIF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIF here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIF.
TP53; BANP; CMTM5; ABI2; C1QBP; C1qbp; ITPR1; BCL2; ATF2