ppif
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  • Official Full Name
  • Peptidylprolyl Isomerase F
  • Background
  • The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
  • Synonyms
  • PPIF; CYP3; Cyp-D; peptidyl-prolyl cis-trans isomerase F, mito-chondrial; PPIase F; rotamase F; cyclophilin 3; cyclophilin D; cyclophilin F; FLJ90798; MGC117207; OTTHUMP00000019925; OTTHUMP00000019926; peptidyl-prolyl cis-trans isomerase, mitochondrial; EC 5.2.1.8; peptidylprolyl isomerase F (cyclophilin F); hCyP3; peptidylprolyl isomerase F
Cat.#:PPIF-1101HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase F, His-tagged
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Cat.#:PPIF-1429HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase F, His-tagged
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Cat.#:PPIF-120HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl isomerase F
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Cat.#:PPIF-159HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIF protein, T7-tagged
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Cat.#:PPIF-27049THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIF
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Cat.#:PPIF-631HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PPIF Protein, His-tagged
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Cat.#:PPIF-817HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase F, T7-tagged
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Cat.#:PPIF-13184MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPIF Protein
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Cat.#:Ppif-7103MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ppif protein, His-tagged
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Cat.#:Ppif-109RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Ppif, His-tagged
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Cat.#:PPIF-4603RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPIF Protein
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Cat.#:PPIF-3547RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPIF Protein, His-tagged
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Cat.#:PPIF-2888CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPIF
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Cat.#:PPIF-2970HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPIF 293 Cell Lysate
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Involved Pathway

PPIF involved in several pathways and played different roles in them. We selected most pathways PPIF participated on our site, such as Calcium signaling pathway, Huntingtons disease, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
ADORA2A; PTK2BB; CALML5; PLCB1; HTR6; P2RX2; ADORA2AA; PRKACA; GRIN2C; SLC8A1B
Huntingtons disease
TGM2; mt-Atp8; ATP5G3; NDUFAB1; VDAC3; COX6B1; NDUFA2; NDUFV2; BDNF; DNAH11
Parkinsons disease
SLC18A1; COX7A2; NDUFS8; UBE2G2; UBE1Y1; LRRK2; NDUFS5; NDUFB5; MT-ND4; NDUFB8
Toxoplasmosis
NOS2; TGFB3; BIRC3; PIK3R5; IRGM; GNAO1; ITGA6; MAP2K3; HLA-DOB; MAPK3
cGMP-PKG signaling pathway
MYH7; PPP1R12A; ATP1A1; IRS2; IRS4; PLCB1; SRF; SLC25A31; FXYD2; CREB3L3

Protein Function

PPIF has several biochemical functions, for example, cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIF itself. We selected most functions PPIF had, and list some proteins which have the same functions with PPIF. You can find most of the proteins on our site.
Function
Related Protein
Function cyclosporin A binding
Related Protein PPIC; PPIE; PPIG; PPIF; PPIH; PPID
Function peptidyl-prolyl cis-trans isomerase activity
Related Protein PPIH; TTC9B; FKBP11; PPIAL4B; PPIE; FKBP8; PIN4; PPID; FKBP1AA; FKBP7
Function protein binding
Related Protein KCND3; CYFIP2; CTRC; TBC1D15; CRADD; GPS2; PPP2R5B; BTG1; PYGO1; NOL12

Interacting Protein

PPIF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIF here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIF.
TP53; BANP; CMTM5; ABI2; C1QBP; C1qbp; ITPR1; BCL2; ATF2