DLL3
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Official Full Name
delta-like 3 (Drosophila)
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Overview
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
DLL3; delta-like 3 (Drosophila); SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cynomolgus
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus macaque
- CHO
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Yeast
- Fc
- FLAG
- His
- Avi
- His (Fc)
- His|SUMO
- flag
- SUMO
- human|IgG1|Fc
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | DLL3-31H | Recombinant Human DLL3 protein, His-tagged | HEK293 | His | Ala27-Leu492 | |
Human | DLL3-1189H | Recombinant Human DLL3 Protein, His-SUMO-tagged | E.coli | His/SUMO | ||
Human | DLL3-856H | Recombinant Human DLL3 Protein, FLAG-tagged | HEK293 | FLAG | aa 27-466 | |
Human | DLL3-30H | Recombinant Human DLL3 protein, Fc-tagged | HEK293 | human/IgG1/Fc | Ala27-Leu492 | |
Human | DLL3-1719H | Recombinant Human DLL3 Protein (27-492 aa), His-tagged | Yeast | His | 27-492 aa | |
Human | DLL3-4885H | Recombinant Human DLL3 protein, His-SUMO-tagged | E.coli | His-SUMO | 27-492aa | |
Human | DLL3-965H | Recombinant Human DLL3 Protein, His-flag-tagged | HEK293 | His-flag | Ala27-Arg491 | |
Human | DLL3-1119H | Recombinant Human DLL3 protein, His-SUMO-tagged | E.coli | His-SUMO | 383-492aa | |
Human | DLL3-1031H | Recombinant Human DLL3 protein(Ala27-Arg490), His-tagged | HEK293 | N-His | Ala27-Arg490 | |
Human | DLL3-1348H | Recombinant Human DLL3 Protein, His-tagged | E.coli | N-His | Ala27-Leu492 | |
Mouse | Dll3-32M | Recombinant Mouse Dll3 protein, Fc-tagged | HEK293 | Fc | ||
Mouse | DLL3-4631M | Active Recombinant Mouse DLL3 protein, His-tagged | HEK293 | His | Ala25-Arg488 | |
Mouse | DLL3-4632M | Recombinant Mouse DLL3 protein, His-tagged | CHO | His | Ala 25 - Arg 488 | |
Rat | DLL3-1888R | Recombinant Rat DLL3 Protein | Mammalian Cell | His | ||
Rat | DLL3-1547R | Recombinant Rat DLL3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | DLL3-1547R-B | Recombinant Rat DLL3 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Cynomolgus | DLL3-2127C | Active Recombinant Cynomolgus DLL3 protein, His-tagged | HEK293 | His | Ala 27 - Arg 490 | |
Cynomolgus | DLL3-1870C | Active Recombinant Cynomolgus DLL3 protein, His & Avi-tagged | HEK293 | His & Avi | Ala 27 - Arg 488 | |
Mus musculus (Mouse) | RFL33772MF | Recombinant Full Length Mouse Delta-Like Protein 3(Dll3) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (33-592) | |
Rattus norvegicus (Rat) | RFL36004RF | Recombinant Full Length Rat Delta-Like Protein 3(Dll3) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (33-589) | |
Rhesus macaque | DLL3-171R | Recombinant Rhesus macaque DLL3 protein, His-tagged | HEK293 | His | It contains Ala27-Arg490. |
- Involved Pathway
- Protein Function
- Interacting Protein
- DLL3 Related Research Area
DLL3 involved in several pathways and played different roles in them. We selected most pathways DLL3 participated on our site, such as Neural Crest Differentiation, Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Neural Crest Differentiation | TXLNB;SOX5;CDH7;ZIC1;MYB;DLX5;SOX10;MIA;DLL3 |
Notch Signaling Pathway | TUBB3;JAG1A;HER6;NOTCH1A;MFAP2;APH1B;NCSTN;EP300;DLA |
DLL3 has several biochemical functions, for example, Notch binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLL3 itself. We selected most functions DLL3 had, and list some proteins which have the same functions with DLL3. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
Notch binding | JAG1A;DLL1;DLL4;HIF1AN;EGFL7;C8orf4;DLL3;JAG1;ADAM17 |
DLL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLL3.
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