"Dll3" Related Products


Recombinant Mouse Dll3 protein, Fc-tagged

Cat.No.: Dll3-32M
Product Overview: Recombinant Mouse Dll3(aa 25-490) fused with the Fc portion of human IgG1 at C-terminal was expressed in HEK293.
Description: DLL3 (Delta-like protein 3; Delta3) inhibits primary neurogenesis. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 binds and activates Notch-1. Defects in DLL3 are the cause of spondylocostal dysostosis type 1 (SCDO1).
Source: HEK293
Species: Mouse
Tag : Fc
Form: Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
Molecular Mass: ~90kDa (SDS-PAGE)
Endotoxin: <0.1EU/μg purified protein (LAL test; Lonza).
Purity: ≥90% (SDS-PAGE)
Storage: Short Term Storage: +4 centigrade;
Long Term Storage: -20 centigrade;
Handling Advice: After opening, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles.
Gene Name: Dll3 delta-like 3 (Drosophila) [ Mus musculus ]
Official Symbol: Dll3
Synonyms: DLL3; delta-like 3 (Drosophila); delta-like protein 3; delta3; M-Delta-3; drosophila Delta homolog 3; pu; pudgy;
Gene ID: 13389
mRNA Refseq: NM_007866
Protein Refseq: NP_031892
UniProt ID: O88516
Chromosome Location: 7 A3; 7 16.67 cM
Pathway: Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem;
Function: Notch binding; Notch binding; protein binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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