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Recombinant Mouse Dll3 protein, Fc-tagged

Cat.No. : Dll3-32M
Product Overview : Recombinant Mouse Dll3(aa 25-490) fused with the Fc portion of human IgG1 at C-terminal was expressed in HEK293.
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Description : DLL3 (Delta-like protein 3; Delta3) inhibits primary neurogenesis. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 binds and activates Notch-1. Defects in DLL3 are the cause of spondylocostal dysostosis type 1 (SCDO1).
Source : HEK293
Species : Mouse
Tag : Fc
Form : Liquid. 0.2μm-filtered solution in PBS, pH 7.2.
Molecular Mass : ~90kDa (SDS-PAGE)
Endotoxin : <0.1EU/μg purified protein (LAL test; Lonza).
Purity : ≥90% (SDS-PAGE)
Storage : Short Term Storage: +4 centigrade;
Long Term Storage: -20 centigrade;
Handling Advice: After opening, prepare aliquots and store at -20 centigrade. Avoid freeze/thaw cycles.
Gene Name : Dll3 delta-like 3 (Drosophila) [ Mus musculus ]
Official Symbol : Dll3
Synonyms : DLL3; delta-like 3 (Drosophila); delta-like protein 3; delta3; M-Delta-3; drosophila Delta homolog 3; pu; pudgy;
Gene ID : 13389
mRNA Refseq : NM_007866
Protein Refseq : NP_031892
UniProt ID : O88516
Chromosome Location : 7 A3; 7 16.67 cM
Pathway : Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch signaling pathway, conserved biosystem;
Function : Notch binding; Notch binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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