|Product Overview :||Recombinant Human DLL3 Protein (Ala 27 - Leu 492) with a human IgG1 Fc tag at the C-terminus is expressed from human 293 cells (HEK293).|
|Description :||This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.|
|Molecular Mass :||75.0 kDa|
|N-terminal Sequence Analysis :||Ala 27|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||>90% as determined by SDS-PAGE.|
|Storage :||For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
4-8 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
|Storage Buffer :||Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.|
Human DLL3, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
|Gene Name :||DLL3 delta like canonical Notch ligand 3 [ Homo sapiens (human) ]|
|Official Symbol :||DLL3|
|Synonyms :||DLL3; delta like canonical Notch ligand 3; SCDO1; delta-like protein 3; delta-like 3; delta3; drosophila Delta homolog 3|
|Gene ID :||10683|
|mRNA Refseq :||NM_016941|
|Protein Refseq :||NP_058637|
|UniProt ID :||Q9NYJ7|