mcm3
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  • Official Full Name
  • minichromosome maintenance complex component 3
  • Background
  • The minichromosome maintenance (MCM) 2-7 proteins are a family of six related proteins required for the initiation and elongation of DNA replication. MCM2-7 bind together to form the heterohexameric MCM complex that is thought to act as a replicative heli
  • Synonyms
  • MCM3; minichromosome maintenance complex component 3; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 3; DNA replication licensing factor MCM3; p102; RLF subunit beta; hRlf beta subunit
Cat.#:MCM3-23HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MCM3, GST-tagged
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Cat.#:MCM3-28038THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MCM3, His-tagged
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Cat.#:Mcm3-1269MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mcm3 protein, His & T7-tagged
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Cat.#:MCM3-9635MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MCM3 Protein
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Cat.#:MCM3-2703RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MCM3 Protein, His-tagged
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Cat.#:MCM3-1563CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MCM3
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Cat.#:MCM3-11847ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MCM3
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Cat.#:MCM3-4419HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MCM3 293 Cell Lysate
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Involved Pathway

MCM3 involved in several pathways and played different roles in them. We selected most pathways MCM3 participated on our site, such as DNA replication, Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA replication
RFC1; GINS3; MCM6L; RFC2; MCM3L; CDT1; POLD1; DNA2; MCM6; MCM2
Cell cycle
CCNB2; ANAPC5; MYCB; CUL1A; RAD21B; BORA; CENPI; PDS5B; TMEM188; PCM1

Protein Function

MCM3 has several biochemical functions, for example, ATP binding, DNA binding, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM3 itself. We selected most functions MCM3 had, and list some proteins which have the same functions with MCM3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PAK2; MAP2K2A; MYO7B; RARS2; CAMK2A; ATP1A3; GCLC; MYLK4; MSH5; TSSK2
Function DNA binding
Related Protein SP140L; H2AFV; GATA5; ZNF668; ENG2B; MYBL2B; NFIL3; MCM8; ONECUT3; YEATS4
Function DNA helicase activity
Related Protein RECQL5; RUVBL2; MCM6L; IGHMBP2; MCM2; MCM5; RUVBL1; MCM3; RECQL; FBXO18
Function protein binding
Related Protein ZNF41; COX17; LDB3; HMGN2; VENTX; PEX13; STX18; OTX2; PQBP1; ESRRG

Interacting Protein

MCM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM3.
MCMBP; MCM2; MCM5

MCM3 Related Articles

Ren, HJ; Liu, RD; et al. Construction and use of a Trichinella spiralis phage display library to identify the interactions between parasite and host enterocytes. PARASITOLOGY RESEARCH 112:1857-1863(2013).
Gan, N; Du, Y; et al. Increase of Mcm3 and Mcm4 expression in cervical squamous cell carcinomas. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 31:291-294(2010).