Active Recombinant Human TXK(256-end) Protein, N-His-tagged
Cat.No. : | TXK-252H |
Product Overview : | N-terminal 6Histagged recombinant human Txk, residues 256–end, expressed by baculovirus in Sf21 insect cells. Purified using Ni2+/NTA agarose. |
- Specification
- Gene Information
- Related Products
Description : | TxK (TxK Tyrosine Kinase) is a ,on-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. It predicted to enable non-membrane spanning protein tyrosine kinase activity. TXK is also involved in positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of macromolecule metabolic process, and protein autophosphorylation. TXK is located in cytoplasm and nucleus. |
Source : | Sf21 |
Species : | Human |
Tag : | His |
Protein length : | 256-end |
Form : | 0.358mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1mM EGTA, 0.1% 2-mercaptoethanol, 0.03% Brij-35. Frozen solution. |
Bio-activity : | 4149U/mg, where one unit of Txk, active activity is defined as 1nmol phosphate incorporated into 250μM (GEEPLYWSFPAKKK) per minute at 30 centigrade with a final ATP concentration of 100μM. |
Molecular Mass : | 35.3 kDa |
AA Sequence : | 1 MSYYHHHHHH DYDIPTTENL YFQGAMDPEF TAGFSYEKWE IDPSELAFIK EIGSGQFGVV 61 HLGEWRSHIQ VAIKAINEGS MSEEDFIEEA KVMMKLSHSK LVQLYGVCIQ RKPLYIVTEF 121 MENGCLLNYL RENKGKLRKE MLLSVCQDIC EGMEYLERNG YIHRDLAARN CLVSSTCIVK 181 ISDFGMTRYV LDDEYVSSFG AKFPIKWSPP EVFLFNKYSS KSDVWSFGVL MWEVFTEGKM 241 PFENKSNLQV VEAISEGFRL YRPHLAPMSI YEVMYSCWHE KPEGRPTFAE LLRAVTEIAE 301 TW |
Purity : | Purity 66.4% by SDS-PAGE and Coomassie staining. |
Applications : | Drug Discovery & Development |
Storage : | 6 months at -70 centigrade. |
Handling Advice : | Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into prechilled micro-centrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70 centigrade. |
Use/Stability : | On receipt of material store at -70 centigrade. Unopened reagent is stable for a minimum of 1 year from date of shipment when stored at recommended storage temperature. Avoid repeat freeze/thaw cycles. For maximum recovery of product, centrifuge original vial prior to removing the cap. |
Gene Name : | TXK TXK tyrosine kinase [ Homo sapiens (human) ] |
Official Symbol : | TXK |
Synonyms : | TXK; TXK tyrosine kinase; RLK; TKL; BTKL; PTK4; PSCTK5 |
Gene ID : | 7294 |
mRNA Refseq : | NM_003328.3 |
Protein Refseq : | NP_003319.2 |
MIM : | 600058 |
UniProt ID : | P42681 |
Products Types
◆ Recombinant Protein | ||
TXK-9781M | Recombinant Mouse TXK Protein, His (Fc)-Avi-tagged | +Inquiry |
TXK-0750H | Recombinant Human TXK Protein (I2-W527), Tag Free | +Inquiry |
TXK-0749H | Recombinant Human TXK Protein (I2-W527), GST tagged | +Inquiry |
Txk-632M | Recombinant Mouse Txk Protein, His-tagged | +Inquiry |
TXK-17648M | Recombinant Mouse TXK Protein | +Inquiry |
◆ Lysates | ||
TXK-713HCL | Recombinant Human TXK lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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