Recombinant Human EZH2 protein, His-tagged
|Product Overview :
|Recombinant Human EZH2 protein(NP_001190176.1)(Glu51~Phe285) was expressed in E. coli with a N-terminal His Tag.
- Gene Information
- Related Products
|This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
|20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
|Molecular Mass :
|28kDa as determined by SDS-PAGE reducing conditions.
|Protein length :
|AA Sequence :
|ERTEILNQEWKQRRIQPVHILTSVS SLRGTRECSVTSDLDFPTQVIPLKT LNAVASVPIMYSWSPLQQNFMVEDE TVLHNIPYMGDEVLDQDGTFIEELI KNYDGKVHGDRECGFINDEIFVELV NALGQYNDDDDDDDGDDPEEREEKQ KDLEDHRDDKESRPPRKFPSDKIFE AISSMFPDKGTAEELKEKYKELTEQ QLPGALPPECTPNIDGPNAKSVQRE QSLHSFHTLF
|<1.0EU per 1µg (determined by the LAL method)
|Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)
|The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures.
|The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
|Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
|Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
|Gene Name :
|Official Symbol :
|ENX-1; KMT6; KMT6A; Histone-lysine N-methyltransferase EZH2; Lysine N-methyltransferase 6
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|◆ Recombinant Protein
|Recombinant Human EZH2 Protein, His-tagged
|Recombinant Mouse Ezh2 Protein, MYC/DDK-tagged
|Recombinant Human EZH2 Protein, His (Fc)-Avi-tagged
|Recombinant Human EZH2 Protein, GST-tagged
|Recombinant Rhesus Macaque EZH2 Protein, His (Fc)-Avi-tagged
|Recombinant Human EZH2 293 Cell Lysate
|◆ Assay kits
|EZH2 (A677G) Chemiluminescent Assay Kit
|EZH2 Chemiluminescent Assay Kit
|EZH2 Homogeneous Assay Kit
|EZH2 (Y641F) Chemiluminescent Assay Kit
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (5)Ask a question
EZH2 overexpression is associated with promoting tumor cell proliferation, invasion, and metastasis, leading to cancer progression.
EZH2 has been implicated in various non-oncological conditions, including cardiovascular diseases and neurodegenerative disorders.
Potential side effects may include hematological toxicity, gastrointestinal issues, and liver enzyme elevation.
Small molecule inhibitors of EZH2 have been developed and are being investigated as potential cancer therapies.
High EZH2 expression has been associated with poor prognosis in several cancer types.
Customer Reviews (3)Write a review
The versatility of the EZH2 protein is truly remarkable, as it can be employed across a wide range of applications in my research.
In addition to its outstanding quality, the manufacturer of the EZH2 protein offers excellent technical support that can effectively address any challenges I may encounter.
Their dedicated team of experts is readily available to provide guidance and assistance, ensuring a seamless integration of the EZH2 protein into my experimental setup.
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