"TBCA" Related Products

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Recombinant Human Tubulin Folding Cofactor A

Cat.No.: TBCA-6925H
Product Overview: Recombinant human TBCA protein was expressed in E. coli and purified by using conventional chromatography techniques. MW: 12.8 kDa.
Description: TBCA is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin in a quasi-native confirmation. This protein is essential for cell viability and its knockdown produces a decrease in the amount of soluble tubulin, modifications in microtubules and G1 cell cycle arrest.
Source: E. coli
Species: Human
Tag: N/A
Form: Liquid. In 20 mM Tris-HCl buffer pH 7.5 containing 1 mM DTT, 10% glycerol.
Molecular Mass: 12.8 kDa (108aa), confirmed by MALDI-TOF.
Protein length: 1-108aa
AA Sequence: MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA
Purity: >95% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1 mg/ml (determined by Bradford assay)
Gene Name: TBCA tubulin folding cofactor A [ Homo sapiens ]
Official Symbol: TBCA
Synonyms: TBCA; tubulin folding cofactor A; tubulin specific chaperone a; tubulin-specific chaperone A; CFA; chaperonin cofactor A; TCP1-chaperonin cofactor A; tubulin-folding cofactor A;
Gene ID: 6902
mRNA Refseq: NM_004607
Protein Refseq: NP_004598
MIM: 610058
UniProt ID: O75347
Chromosome Location: 5q14.1
Pathway: Metabolism of proteins, organism-specific biosystem; Post-chaperonin tubulin folding pathway, organism-specific biosystem; Protein folding, organism-specific biosystem;
Function: chaperone binding; unfolded protein binding;

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