Recombinant Human Sulfotransferase Family, Cytosolic, 2B, Member 1

• Cat.No.: SULT2B1-1473H
• Product Overview: SULT2B1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 365 amino acids (1-365 a.a.) and having a molecular mass of 41.3 kDa. SULT2B1 protein is purified by standard chromatography.

Specification

• Cat. No.: SULT2B1-1473H
• Description: SULT2B1 catalyzes the sulfate conjugation of numerous hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation enhances the water solubility of molecules, and therefore their renal excretion, however it can also result in bioactivation to form active metabolites. SULT2B1b is localized in the cytosol and nuclei of human cells. SULT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and participates in cholesterol sulfation in human skin.
• Source: Human
• Host: Escherichia Coli.
• Form: (SULT2B1 Human solution containing 20mM Trsi HCL pH-7.5, & 10% glycerol.
• Purity: Greater than 85.0% as determined by SDS-PAGE
• Physical Appearance: Sterile Filtered colorless solution.
• Amino acid sequence: MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPS WIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFL KGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRG AFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETP HPRPS.
• Storage: SULT2B1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles

Gene Information

• Gene Name: SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 [ Homo sapiens ]
• Official Symbol: SULT2B1
• Synonyms: SULT2B1; sulfotransferase family, cytosolic, 2B, member 1; HSST2; sulfotransferase family cytosolic 2B member 1; ST2B1; sulfotransferase 2B1; alcohol sulfotransferase; hydroxysteroid sulfotransferase 2; Hydroxysteroid sulfotransferase 2; Sulfotransferase 2B1; Alcohol sulfotransferase; EC 2.8.2.2
• Gene ID: 6820
• mRNA Refseq: NM_004605
• Protein Refseq: NP_004596
• MIM: 604125
• UniProt ID: O00204
• Chromosome Location: 19q13.3
• Pathway: Steroid hormone biosynthesis; Sulfur metabolism; Biological oxidations
• Function: alcohol sulfotransferase activity; protein binding; steroid sulfotransferase activity; transferase activity